5-acetamido-4-hydroxy-2-phenoxy-6-(1,2,3-trihydroxypropyl)oxane-2-carboxylic Acid

Base Information

Chemical Name:5-acetamido-4-hydroxy-2-phenoxy-6-(1,2,3-trihydroxypropyl)oxane-2-carboxylic Acid
CAS No.:15964-32-6
Molecular Formula:C₁₇H₂₃NO₉
Molecular Weight:385.371
Hs Code.:29329990
DSSTox Substance ID:DTXSID90400752
Mol file:15964-32-6.mol

Synonyms:15964-32-6;5-acetamido-4-hydroxy-2-phenoxy-6-(1,2,3-trihydroxypropyl)oxane-2-carboxylic Acid;2-O-Phenyl-alpha-D-N-acetylneuraminic acid;DTXSID90400752;2-O-Phenyl- alpha -D-N-acetylneuraminic acid;2-O-Phenyl-alpha-D-N-acetylneuraminic acid, synthetic, ~95%

Suppliers and Price of 5-acetamido-4-hydroxy-2-phenoxy-6-(1,2,3-trihydroxypropyl)oxane-2-carboxylic Acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
2-O-Phenyl a-D-N-acetylneuraminic acid
1mg
$ 409.00

American Custom Chemicals Corporation
2-O-PHENYL A-D-N-ACETYLNEURAMINIC ACID 95.00%
5MG
$ 495.66

Total 4 raw suppliers

Chemical Property of 5-acetamido-4-hydroxy-2-phenoxy-6-(1,2,3-trihydroxypropyl)oxane-2-carboxylic Acid

Chemical Property:

Vapor Pressure:4.5E-26mmHg at 25°C
Refractive Index:1.626
Boiling Point:786.7°C at 760 mmHg
Flash Point:429.6°C
PSA：165.78000
Density:1.5g/cm³
LogP:-1.39420
Storage Temp.:−20°C
XLogP3:-1.1
Hydrogen Bond Donor Count:6
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:7
Exact Mass:385.13728131
Heavy Atom Count:27
Complexity:525

Purity/Quality:

97% ^*data from raw suppliers

2-O-Phenyl a-D-N-acetylneuraminic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)NC1C(CC(OC1C(C(CO)O)O)(C(=O)O)OC2=CC=CC=C2)O

Technology Process of 5-acetamido-4-hydroxy-2-phenoxy-6-(1,2,3-trihydroxypropyl)oxane-2-carboxylic Acid

There total 3 articles about 5-acetamido-4-hydroxy-2-phenoxy-6-(1,2,3-trihydroxypropyl)oxane-2-carboxylic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 6770-41-8,59367-09-8,67670-69-3,132883-18-2,147129-74-6
Methyl (5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-β-D-glycero-D-galacto-2-nonulopyranosyl chloride)onate

: 15964-32-6
(Phenyl 5-acetamido-3,5-dideoxy-α-D-glycero-D-galacto-2-nonulopyranosid)onic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 62 percent / aq. NaOH / benzyltriethylammonium chloride / CHCl₃ / 0.5 h / Heating

2: 1.) sodium methoxide, 2.) aq. NaOH / 1.) MeOH, RT, 2 h; 2.) RT, 0.5 h

With sodium hydroxide; sodium methylate; N-benzyl-N,N,N-triethylammonium chloride; In chloroform;
DOI:10.1016/0008-6215(90)84104-3

Reference yield:

: 108-95-2,27073-41-2
phenol

: 15964-32-6
(Phenyl 5-acetamido-3,5-dideoxy-α-D-glycero-D-galacto-2-nonulopyranosid)onic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 62 percent / aq. NaOH / benzyltriethylammonium chloride / CHCl₃ / 0.5 h / Heating

2: 1.) sodium methoxide, 2.) aq. NaOH / 1.) MeOH, RT, 2 h; 2.) RT, 0.5 h

With sodium hydroxide; sodium methylate; N-benzyl-N,N,N-triethylammonium chloride; In chloroform;
DOI:10.1016/0008-6215(90)84104-3

Reference yield:

: 128678-36-4
Methyl (phenyl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-α-D-glycero-D-galacto-2-nonulopyranosid)onate

: 15964-32-6
(Phenyl 5-acetamido-3,5-dideoxy-α-D-glycero-D-galacto-2-nonulopyranosid)onic acid

Guidance literature:: With sodium hydroxide; sodium methylate; Yield given. Multistep reaction; 1.) MeOH, RT, 2 h; 2.) RT, 0.5 h;
DOI:10.1016/0008-6215(90)84104-3