N'-(3,5-difluoro-4-(hydroxymethyl)phenylsulfonyl)-N,N-dimethylformimidamide

Base Information

Chemical Name:N'-(3,5-difluoro-4-(hydroxymethyl)phenylsulfonyl)-N,N-dimethylformimidamide
CAS No.:1239964-27-2
Molecular Formula:C₁₀H₁₂F₂N₂O₃S
Molecular Weight:278.28
Hs Code.:

Synonyms:N'-(3,5-difluoro-4-(hydroxymethyl)phenylsulfonyl)-N,N-dimethylformimidamide

Suppliers and Price of N'-(3,5-difluoro-4-(hydroxymethyl)phenylsulfonyl)-N,N-dimethylformimidamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of N'-(3,5-difluoro-4-(hydroxymethyl)phenylsulfonyl)-N,N-dimethylformimidamide

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

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Hazard Codes:

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Technology Process of N'-(3,5-difluoro-4-(hydroxymethyl)phenylsulfonyl)-N,N-dimethylformimidamide

There total 4 articles about N'-(3,5-difluoro-4-(hydroxymethyl)phenylsulfonyl)-N,N-dimethylformimidamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1239964-26-1
N'-(3,5-difluoro-4-formylphenylsulfonyl)-N,N-dimethylformimidamide

: 1239964-27-2
N'-(3,5-difluoro-4-(hydroxymethyl)phenylsulfonyl)-N,N-dimethylformimidamide

Guidance literature:: With sodium tetrahydroborate; In methanol; at 0 ℃; for 1h;

Reference yield:

: 210532-25-5
3,5-difluorobenzenesulfonyl chloride

: 1239964-27-2
N'-(3,5-difluoro-4-(hydroxymethyl)phenylsulfonyl)-N,N-dimethylformimidamide

Guidance literature:: Multi-step reaction with 4 steps

1.1: ammonium hydroxide / water; tetrahydrofuran / 1 h / Cooling with ice

2.1: acetonitrile / 1 h

3.1: diisopropylamine; n-butyllithium / hexane; tetrahydrofuran / 3 h / -78 °C

3.2: 0.5 h / -78 °C

4.1: sodium tetrahydroborate / methanol / 1 h / 0 °C

With ammonium hydroxide; sodium tetrahydroborate; n-butyllithium; diisopropylamine; In tetrahydrofuran; methanol; hexane; water; acetonitrile;

Reference yield:

: 140480-89-3
3,5-difluorobenzenesulfonamide

: 1239964-27-2
N'-(3,5-difluoro-4-(hydroxymethyl)phenylsulfonyl)-N,N-dimethylformimidamide

Guidance literature:: Multi-step reaction with 3 steps

1.1: acetonitrile / 1 h

2.1: diisopropylamine; n-butyllithium / hexane; tetrahydrofuran / 3 h / -78 °C

2.2: 0.5 h / -78 °C

3.1: sodium tetrahydroborate / methanol / 1 h / 0 °C

With sodium tetrahydroborate; n-butyllithium; diisopropylamine; In tetrahydrofuran; methanol; hexane; acetonitrile;