Technology Process of C46H48N6O6
There total 10 articles about C46H48N6O6 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: pyridine; hydroxylamine hydrochloride / 60 °C / Inert atmosphere
2: N-ethyl-N,N-diisopropylamine / ethyl acetate / Inert atmosphere
3: trifluoroacetic acid / dichloromethane / 20 °C / Inert atmosphere
4: 4-methyl-morpholine / tetrahydrofuran / 0.25 h / -15 °C / Inert atmosphere
5: 4-methyl-morpholine / tetrahydrofuran; ethyl acetate / -15 °C / Inert atmosphere
With
4-methyl-morpholine; pyridine; hydroxylamine hydrochloride; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid;
In
tetrahydrofuran; dichloromethane; ethyl acetate;
DOI:10.1021/jm200608k
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: benzotriazol-1-ol; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate / dichloromethane / 0.25 h / 20 °C / Inert atmosphere
1.2: 3 h / Inert atmosphere
2.1: trifluoroacetic acid / dichloromethane / 20 °C / Inert atmosphere
2.2: 1 h / Inert atmosphere
3.1: 4-methyl-morpholine / tetrahydrofuran; ethyl acetate / -15 °C / Inert atmosphere
With
4-methyl-morpholine; benzotriazol-1-ol; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; trifluoroacetic acid;
In
tetrahydrofuran; dichloromethane; ethyl acetate;
DOI:10.1021/jm200608k
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: trifluoroacetic acid / dichloromethane / 20 °C / Inert atmosphere
1.2: 1 h / Inert atmosphere
2.1: 4-methyl-morpholine / tetrahydrofuran; ethyl acetate / -15 °C / Inert atmosphere
With
4-methyl-morpholine; trifluoroacetic acid;
In
tetrahydrofuran; dichloromethane; ethyl acetate;
DOI:10.1021/jm200608k