benzhydrylidene aza-phenylalaninyl-proline tert-butyl ester

Base Information

• Chemical Name: benzhydrylidene aza-phenylalaninyl-proline tert-butyl ester
• CAS No.: 1234782-89-8
• Molecular Formula: C₃₀H₃₃N₃O₃
• Molecular Weight: 483.61
• Mol file: 1234782-89-8.mol

Synonyms:benzhydrylidene aza-phenylalaninyl-proline tert-butyl ester

Chemical Property of benzhydrylidene aza-phenylalaninyl-proline tert-butyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of benzhydrylidene aza-phenylalaninyl-proline tert-butyl ester

There total 1 articles about benzhydrylidene aza-phenylalaninyl-proline tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

benzhydrylidene aza-glycinyl-proline tert-butyl ester (1234783-06-2) + benzyl bromide (100-39-0) → benzhydrylidene aza-phenylalaninyl-proline tert-butyl ester (1234782-89-8)

Guidance literature:

benzhydrylidene aza-glycinyl-proline tert-butyl ester; With potassium tert-butylate; In tetrahydrofuran; at 0 ℃; for 0.25h; Inert atmosphere;

benzyl bromide; In tetrahydrofuran; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1002/psc.1235

Reference yield: 88.0%

benzhydrylidene aza-phenylalaninyl-proline tert-butyl ester (1234782-89-8) → aza-phenylalaninyl-proline tert-butyl ester (84766-98-3)

Guidance literature:

With pyridine; hydroxylamine hydrochloride; at 60 ℃; for 12h; Inert atmosphere;

DOI:10.1002/psc.1235

Reference yield: 88.0%

benzhydrylidene aza-phenylalaninyl-proline tert-butyl ester (1234782-89-8) → aza-phenylalaninylproline tert-butyl ester (1329063-51-5)

Guidance literature:

With pyridine; hydroxylamine hydrochloride; at 60 ℃; Inert atmosphere;

DOI:10.1021/jm200608k

upstream raw materials:

benzhydrylidene aza-glycinyl-proline tert-butyl ester

benzyl bromide

Downstream raw materials:

benzhydrylidene aza-phenylalaninyl-proline diphenylmethylamide

aza-phenylalaninyl-proline tert-butyl ester

N-Fmoc-(2S)-alanyl-aza-phenylalanyl-(2S)-prolyl-tert-butyl ester

(S,R)-Fmoc-alaninyl-aza-phenylalaninyl-proline tert-butyl ester