2-(4-fluoro-benzenesulfonyl)-2-methyl-propionic acid hydrazide

Base Information

• Chemical Name: 2-(4-fluoro-benzenesulfonyl)-2-methyl-propionic acid hydrazide
• CAS No.: 1196104-10-5
• Molecular Formula: C₁₀H₁₃FN₂O₃S
• Molecular Weight: 260.289
• Mol file: 1196104-10-5.mol

Synonyms:2-(4-fluoro-benzenesulfonyl)-2-methyl-propionic acid hydrazide

Chemical Property of 2-(4-fluoro-benzenesulfonyl)-2-methyl-propionic acid hydrazide

Chemical Property:

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Technology Process of 2-(4-fluoro-benzenesulfonyl)-2-methyl-propionic acid hydrazide

There total 1 articles about 2-(4-fluoro-benzenesulfonyl)-2-methyl-propionic acid hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

→ 2-(4-fluoro-benzenesulfonyl)-2-methyl-propionic acid hydrazide (1196104-10-5)

Guidance literature:

Reference yield: 39.0%

2-(4-fluoro-benzenesulfonyl)-2-methyl-propionic acid hydrazide (1196104-10-5) + 3-tert-butylisoxazole-5-carboxylic acid (133674-40-5) → 3-tert-butyl-isoxazole-5-carboxylic acid N'-[2-(4-fluoro-benzenesulfonyl)-2-methyl-propionyl]-hydrazide (1196104-30-9)

Guidance literature:

With pyridine; trichlorophosphate; at 0 ℃;

Reference yield: 34.0%

3-tert-butyl-isoxazole-5-carbonyl chloride (1196104-05-8) + 2-(4-fluoro-benzenesulfonyl)-2-methyl-propionic acid hydrazide (1196104-10-5) → 2-(3-tert-butyl-isoxazol-5-yl)-5-[1-(4-fluoro-benzenesulfonyl)-1-methyl-ethyl]-[1,3,4]oxadiazole (1196103-48-6)

Guidance literature:

With trichlorophosphate; at 100 ℃; for 3h; Sealed tube;

Downstream raw materials:

3-tert-butyl-isoxazole-5-carboxylic acid N'-[2-(4-fluoro-benzenesulfonyl)-2-methyl-propionyl]-hydrazide

2-(3-tert-butyl-isoxazol-5-yl)-5-[1-(4-fluoro-benzenesulfonyl)-1-methyl-ethyl]-[1,3,4]oxadiazole