C₄₁H₄₃F₄N₃O₅

Base Information

Chemical Name:C₄₁H₄₃F₄N₃O₅
CAS No.:1609377-85-6
Molecular Formula:C₄₁H₄₃F₄N₃O₅
Molecular Weight:733.803
Hs Code.:

C<sub>41</sub>H<sub>43</sub>F<sub>4</sub>N<sub>3</sub>O<sub>5</sub>

Synonyms:C₄₁H₄₃F₄N₃O₅

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C₄₁H₄₃F₄N₃O₅

Chemical Property:

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Technology Process of C₄₁H₄₃F₄N₃O₅

There total 10 articles about C₄₁H₄₃F₄N₃O₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 869203-36-1
2-fluoro-3-methoxycarbonylbenzoic acid chloride

: 1609377-84-5
C₃₂H₃₈F₃N₃O₂

: 1609377-85-6
C₄₁H₄₃F₄N₃O₅

Guidance literature:: With triethylamine; In tetrahydrofuran; at 0 - 20 ℃; for 2h; Inert atmosphere;
DOI:10.1002/chem.201304161

Reference yield:

: 914301-44-3
2-fluoroisophthalic acid monomethyl ester

: 1609377-85-6
C₄₁H₄₃F₄N₃O₅

Guidance literature:: Multi-step reaction with 2 steps

1: oxalyl dichloride; N,N-dimethyl-formamide / tetrahydrofuran / 0.5 h / 0 °C / Inert atmosphere

2: triethylamine / tetrahydrofuran / 2 h / 0 - 20 °C / Inert atmosphere

With oxalyl dichloride; triethylamine; N,N-dimethyl-formamide; In tetrahydrofuran;
DOI:10.1002/chem.201304161

Reference yield:

: 1609377-82-3
C₁₈H₂₇ClN₂O₄

: 1609377-85-6
C₄₁H₄₃F₄N₃O₅

Guidance literature:: Multi-step reaction with 4 steps

1: potassium fluoride; 18-crown-6 ether / tetrahydrofuran / 36 h / Reflux; Inert atmosphere

2: 5%-palladium/activated carbon; hydrogen / methanol / 24 h / 760.05 Torr / Inert atmosphere

3: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap / dichloromethane / 12 h / 20 °C / Inert atmosphere

4: triethylamine / tetrahydrofuran / 2 h / 0 - 20 °C / Inert atmosphere

With dmap; potassium fluoride; 18-crown-6 ether; 5%-palladium/activated carbon; hydrogen; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In tetrahydrofuran; methanol; dichloromethane;
DOI:10.1002/chem.201304161