914301-44-3

Usage

Uses

Used in Chemical Synthesis:
1,3-Benzenedicarboxylic acid, 2-fluoro-, 1-methyl ester is used as a reagent for the preparation of aromatic amides and artificial hybrid helices. Its unique structure allows it to serve as a valuable building block in the synthesis of complex organic molecules and materials.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 1,3-Benzenedicarboxylic acid, 2-fluoro-, 1-methyl ester is used as an intermediate in the synthesis of various drug candidates. Its presence of a fluorine atom and a methyl ester group can impart specific properties to the final drug molecules, such as improved pharmacokinetics and enhanced biological activity.
Used in Material Science:
1,3-Benzenedicarboxylic acid, 2-fluoro-, 1-methyl ester can also be utilized in the development of new materials with unique properties. Its incorporation into polymers or other materials can lead to the creation of novel materials with improved characteristics, such as increased stability, enhanced mechanical properties, or specific optical or electronic properties.

Upstream product

• 67-56-1 methanol 
• 1583-65-9 2-fluoro-isophthalic acid 
• 723334-03-0 2-fluoro-isophthalic acid dimethyl ester 
• 91129-30-5 2-fluoroisophthalic acid dichloride 
• 443-88-9 2-fluoro-m-xylene 

Downstream Products

• 869203-36-1 2-fluoro-3-methoxycarbonylbenzoic acid chloride 
• 1042055-86-6 methyl 3-((tert-butoxycarbonyl)amino)-2-fluorobenzoate 
• 1260236-43-8 methyl 2-fluoro-3-(piperidine-1-carbonyl)benzoate 
• 1042055-88-8 3-amino-2-fluorobenzoic acid trifluoroacetate 
• 1609377-74-3 C₃₇H₄₇F₃N₄O₃ 
• 1609378-03-1 C₆₅H₈₁F₅N₆O₆ 
• 1609377-96-9 C₃₉H₄₉F₃N₄O₄ 
• 1609378-01-9 C₄₇H₅₀F₃N₃O₅ 
• 1609378-00-8 C₃₈H₄₅F₂N₃O₂ 
• 1609377-73-2 C₁₄H₉F₂NO₃ 
• 1609377-99-2 C₂₁H₁₈FNO₃ 
• 1609377-94-7 C₄₇H₅₀F₃N₃O₅ 
• 1609377-93-6 C₃₈H₄₅F₂N₃O₂ 
• 1609377-92-5 C₂₁H₁₈FNO₃ 

Relevant academic research and scientific papers

METHOD FOR PREPARING TRICYCLIC DERIVATIVES

The present invention relates to a method for preparing a tricyclic derivative, and more particulary, to a method for preparing a tricyclic derivative inetermediate with high yield and purity, the method including: introducing a hydroxy group by esterifyi

METHOD FOR PREPARING TRICYCLIC DERIVATIVES

The present invention relates to a method for preparing a tricyclic derivative, and more particulary, to a method for preparing a tricyclic derivative inetermediate with high yield and purity, the method including: introducing a hydroxy group by esterifyi

Potent non-benzoquinone ansamycin heat shock protein 90 inhibitors from genetic engineering of Streptomyces hygroscopicus

Inhibition of the protein chaperone Hsp90 is a promising new approach to cancer therapy. We describe the preparation of potent non-benzoquinone ansamycins. One of these analogues, generated by feeding 3-amino-5-chlorobenzoic acid to a genetically engineer

Macrolactams by engineered biosynthesis

Macrolactams are made by feeding aromatic amino acids as replacement starter units to a mutant strain of the geldanamycin-producing microorganism Streptomyces hygroscopicus var. geldanus NRRL 3602, wherein the gene cluster encoding enzymes for the biosynt

Design, synthesis, and incorporation of a β-turn mimetic in angiotensin II forming novel pseudopeptides with affinity for AT1 and AT2 receptors

A benzodiazepine-based β-turn mimetic has been designed, synthesized, and incorporated into angiotensin II. Comparison of the mimetic with β-turns in crystallized proteins showed that it most closely resembles a type II β-turn. The compounds exhibited hig