N-(pyrazin-2-yl)benzimidamide

Base Information

Chemical Name:N-(pyrazin-2-yl)benzimidamide
CAS No.:144658-01-5
Molecular Formula:C₁₁H₁₀N₄
Molecular Weight:198.227
Hs Code.:

Synonyms:N-(pyrazin-2-yl)benzimidamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-(pyrazin-2-yl)benzimidamide

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Technology Process of N-(pyrazin-2-yl)benzimidamide

There total 3 articles about N-(pyrazin-2-yl)benzimidamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 5049-61-6
2-Aminopyrazine

: 100-47-0
benzonitrile

: 144658-01-5
N-(pyrazin-2-yl)benzimidamide

Guidance literature:: 2-Aminopyrazine; With potassium tert-butylate; In dimethyl sulfoxide; at 20 ℃; for 0.25h; Inert atmosphere;

benzonitrile; In dimethyl sulfoxide; at 20 - 50 ℃;
DOI:10.1021/acs.joc.5b01183

Reference yield:

: 5049-61-6
2-Aminopyrazine

: 100-47-0
benzonitrile

: 144658-01-5
N-(2-pyrazinyl)benzamidine

Guidance literature:: With lithium diisopropyl amide; Yield given. Multistep reaction; 1.) THF, DMSO, a) -40 deg C, b) 0 deg C, 30 min, 2.) a) -20 deg C, b) room temperature, 17 h;
DOI:10.1016/S0040-4020(01)90374-6