NTR-N₁A₁B₄

Base Information

• Chemical Name: NTR-N₁A₁B₄
• CAS No.: 1449309-35-6
• Molecular Formula: C₂₁H₂₄N₂O₃
• Molecular Weight: 352.433
• Mol file: 1449309-35-6.mol

Synonyms:NTR-N₁A₁B₄

Chemical Property of NTR-N₁A₁B₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of NTR-N₁A₁B₄

There total 3 articles about NTR-N₁A₁B₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-Cyclohexyl-N-(2-phenylethyl)amine (51827-40-8) + m-nitrobenzoic acid chloride (121-90-4) → NTR-N1A1B4 (1449309-35-6)

Guidance literature:

With dmap; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; Inert atmosphere;

DOI:10.1016/j.tet.2013.05.079

Reference yield:

phenylacetaldehyde (122-78-1) → NTR-N1A1B4 (1449309-35-6)

Guidance literature:

Multi-step reaction with 2 steps

1.1: methanol / 3 h / 64 °C

1.2: 5 h / 20 - 64 °C

2.1: dmap; N-ethyl-N,N-diisopropylamine / dichloromethane / 20 °C / Inert atmosphere

With dmap; N-ethyl-N,N-diisopropylamine; In methanol; dichloromethane; 1.1: |Borch Reduction / 1.2: |Borch Reduction;

DOI:10.1016/j.tet.2013.05.079

Reference yield:

cyclohexylamine (108-91-8,157973-60-9) → NTR-N1A1B4 (1449309-35-6)

Guidance literature:

Multi-step reaction with 2 steps

1.1: methanol / 3 h / 64 °C

1.2: 5 h / 20 - 64 °C

2.1: dmap; N-ethyl-N,N-diisopropylamine / dichloromethane / 20 °C / Inert atmosphere

With dmap; N-ethyl-N,N-diisopropylamine; In methanol; dichloromethane; 1.1: |Borch Reduction / 1.2: |Borch Reduction;

DOI:10.1016/j.tet.2013.05.079

upstream raw materials:

phenylacetaldehyde

N-Cyclohexyl-N-(2-phenylethyl)amine

m-nitrobenzoic acid chloride

cyclohexylamine