2-Acetyl-4-methylsalicylicacid

Base Information

• Chemical Name: 2-Acetyl-4-methylsalicylicacid
• CAS No.: 14504-07-5
• Molecular Formula: C10H10 O4
• Molecular Weight: 194.187
• Hs Code.: 2918990090
• Mol file: 14504-07-5.mol

Synonyms:2,4-Cresoticacid, acetate (8CI)

Chemical Property of 2-Acetyl-4-methylsalicylicacid

Chemical Property:

• PSA: 63.60000
• Density: 1.245
• LogP: 1.61850

Purity/Quality:

98%Min ^*data from raw suppliers

2-(acetyloxy)-4-methylbenzoicacid ^*data from reagent suppliers

Safty Information:

• Pictogram(s): R36/37/38:Irritating to eyes, respiratory system and skin.
• Hazard Codes: R36/37/38:Irritating to eyes, respiratory system and skin.
• Statements: R36/37/38:Irritating to eyes, respiratory system and skin.
• Safety Statements: S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.; S36:Wear suitable prot

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Acetyl-4-methylsalicylicacid

There total 3 articles about 2-Acetyl-4-methylsalicylicacid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

2-hydroxy-p-toluic acid (50-85-1) + acetic anhydride (108-24-7) → 2-acetoxy-4-methylbenzoic acid (14504-07-5)

Guidance literature:

With sulfuric acid; at 20 ℃; for 1h; Inert atmosphere;

Reference yield:

2-hydroxy-p-toluic acid (50-85-1) + acetyl chloride (75-36-5) → 2-acetoxy-4-methylbenzoic acid (14504-07-5)

Guidance literature:

Reference yield:

→ 2-acetoxy-4-methylbenzoic acid (14504-07-5)

Guidance literature:

2-Hydroxy-4-methyl-benzoesaeure, Ac2O, c. H2SO4, Δ;

upstream raw materials:

2-hydroxy-p-toluic acid

acetic anhydride

acetyl chloride

Downstream raw materials:

2-acetoxy-4-methyl-benzoyl chloride

4-amino-2-imino-8-methyl-1,2-dihydro-5H-chromeno[2,3-d]pyrimidin-5-one

4-imino-8-methyl-3-phenyl-2-thioxo-1,2,3,4-tetrahydro-5H-chromeno[2,3-d]pyrimidine-5-one

2-(2-hydroxy-4-methylbenzamido)-4-phenylbenzoic acid