isopropyl 4-(5-cyano-4-((2-fluoro-4-(2H-tetrazol-5-yl)phenoxy)methyl)-1H-pyrazol-1-yl)piperidine-1-carboxylate

Base Information

Chemical Name:isopropyl 4-(5-cyano-4-((2-fluoro-4-(2H-tetrazol-5-yl)phenoxy)methyl)-1H-pyrazol-1-yl)piperidine-1-carboxylate
CAS No.:1258001-75-0
Molecular Formula:C₂₁H₂₃FN₈O₃
Molecular Weight:454.464
Hs Code.:

Synonyms:isopropyl 4-(5-cyano-4-((2-fluoro-4-(2H-tetrazol-5-yl)phenoxy)methyl)-1H-pyrazol-1-yl)piperidine-1-carboxylate

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Chemical Property of isopropyl 4-(5-cyano-4-((2-fluoro-4-(2H-tetrazol-5-yl)phenoxy)methyl)-1H-pyrazol-1-yl)piperidine-1-carboxylate

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Technology Process of isopropyl 4-(5-cyano-4-((2-fluoro-4-(2H-tetrazol-5-yl)phenoxy)methyl)-1H-pyrazol-1-yl)piperidine-1-carboxylate

There total 10 articles about isopropyl 4-(5-cyano-4-((2-fluoro-4-(2H-tetrazol-5-yl)phenoxy)methyl)-1H-pyrazol-1-yl)piperidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1258001-77-2
isopropyl 4-(5-cyano-4-((2-fluoro-4-(2-((2-(trimethylsilyl)ethoxy)methyl)-2H-tetrazol-5-yl)phenoxy)methyl)-1H-pyrazol-1-yl)piperidine-1-carboxylate

: 1258001-76-1
isopropyl 4-(5-cyano-4-((2-fluoro-4-(1-((2-(trimethylsilyl)ethoxy)methyl)-1H-tetrazol-5-yl)phenoxy)methyl)-1H-pyrazol-1-yl)piperidine-1-carboxylate

: 1258001-75-0
isopropyl 4-(5-cyano-4-((2-fluoro-4-(2H-tetrazol-5-yl)phenoxy)methyl)-1H-pyrazol-1-yl)piperidine-1-carboxylate

: 1258001-75-0
isopropyl 4-(5-cyano-4-((2-fluoro-4-(1H-tetrazol-5-yl)phenoxy)methyl)-1H-pyrazol-1-yl)piperidine-1-carboxylate

Guidance literature:: With hydrogenchloride; water; In ethanol; at 50 ℃; for 4h;

Reference yield:

: 1258001-77-2
isopropyl 4-(5-cyano-4-((2-fluoro-4-(2-((2-(trimethylsilyl)ethoxy)methyl)-2H-tetrazol-5-yl)phenoxy)methyl)-1H-pyrazol-1-yl)piperidine-1-carboxylate

: 1258001-76-1
isopropyl 4-(5-cyano-4-((2-fluoro-4-(1-((2-(trimethylsilyl)ethoxy)methyl)-1H-tetrazol-5-yl)phenoxy)methyl)-1H-pyrazol-1-yl)piperidine-1-carboxylate

: 1258001-75-0
isopropyl 4-(5-cyano-4-((2-fluoro-4-(2H-tetrazol-5-yl)phenoxy)methyl)-1H-pyrazol-1-yl)piperidine-1-carboxylate

: 1258001-75-0
isopropyl 4-(5-cyano-4-((2-fluoro-4-(1H-tetrazol-5-yl)phenoxy)methyl)-1H-pyrazol-1-yl)piperidine-1-carboxylate

Guidance literature:: With hydrogenchloride; water; In ethanol; at 50 ℃; for 4h;

Reference yield:

: 1258001-28-3
5-(4-(benzyloxy)-3-fluorophenyl)-1H-tetrazole

: 1258001-12-5
isopropyl 4-[5-cyano-4-(hydroxymethyl)-1H-pyrazol-1-yl]piperidine-1-carboxylate

: 76513-69-4
(2-trimethylethylsilylethoxy)methyl chloride

: 1258001-75-0
isopropyl 4-(5-cyano-4-((2-fluoro-4-(1H-tetrazol-5-yl)phenoxy)methyl)-1H-pyrazol-1-yl)piperidine-1-carboxylate

Guidance literature:: 5-(4-(benzyloxy)-3-fluorophenyl)-1H-tetrazole; With sodium hydride; In tetrahydrofuran; mineral oil; at 20 ℃; for 0.25h;

(2-trimethylethylsilylethoxy)methyl chloride; In tetrahydrofuran; mineral oil; at 20 ℃; for 16h;

isopropyl 4-[5-cyano-4-(hydroxymethyl)-1H-pyrazol-1-yl]piperidine-1-carboxylate;