1-O-(tert-butyldiphenylsilyl)-2-O-(4-methoxybenzyl)-sn-glyceryl 2,3,4-tri-O-benzyl-α-D-glucopyranosiduronic acid

Base Information

Chemical Name:1-O-(tert-butyldiphenylsilyl)-2-O-(4-methoxybenzyl)-sn-glyceryl 2,3,4-tri-O-benzyl-α-D-glucopyranosiduronic acid
CAS No.:1421868-59-8
Molecular Formula:C₅₄H₆₀O₁₀Si
Molecular Weight:897.15
Hs Code.:

Synonyms:1-O-(tert-butyldiphenylsilyl)-2-O-(4-methoxybenzyl)-sn-glyceryl 2,3,4-tri-O-benzyl-α-D-glucopyranosiduronic acid

Suppliers and Price of 1-O-(tert-butyldiphenylsilyl)-2-O-(4-methoxybenzyl)-sn-glyceryl 2,3,4-tri-O-benzyl-α-D-glucopyranosiduronic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-O-(tert-butyldiphenylsilyl)-2-O-(4-methoxybenzyl)-sn-glyceryl 2,3,4-tri-O-benzyl-α-D-glucopyranosiduronic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-O-(tert-butyldiphenylsilyl)-2-O-(4-methoxybenzyl)-sn-glyceryl 2,3,4-tri-O-benzyl-α-D-glucopyranosiduronic acid

There total 8 articles about 1-O-(tert-butyldiphenylsilyl)-2-O-(4-methoxybenzyl)-sn-glyceryl 2,3,4-tri-O-benzyl-α-D-glucopyranosiduronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 1421868-58-7
1-O-tert-butyldiphenylsilyl-2-O-(4-methoxybenzyl)-3-O-(2,3,4-tri-O-benzyl-α-D-glucopyranosyl)-sn-glyceride

: 1421868-59-8
1-O-(tert-butyldiphenylsilyl)-2-O-(4-methoxybenzyl)-sn-glyceryl 2,3,4-tri-O-benzyl-α-D-glucopyranosiduronic acid

Guidance literature:: With 2,2,6,6-tetramethyl-piperidine-N-oxyl; [bis(acetoxy)iodo]benzene; In dichloromethane; water; at 20 ℃; for 3h;
DOI:10.1021/jo302508e

Reference yield:

: 866454-44-6
(2R)-3-[(tert-butyldiphenylsilyl)oxy]-2-(4-methoxybenzyloxy)propanal

: 1421868-59-8
1-O-(tert-butyldiphenylsilyl)-2-O-(4-methoxybenzyl)-sn-glyceryl 2,3,4-tri-O-benzyl-α-D-glucopyranosiduronic acid

Guidance literature:: Multi-step reaction with 4 steps

1: sodium tetrahydroborate / water; ethanol / 2 h / 0 °C

2: tetra-(n-butyl)ammonium iodide; 2,4,6-tri-tert-butylpyrimidine / dichloromethane / 144 h / 20 °C / Molecular sieve; Inert atmosphere

3: sodium methylate / methanol; dichloromethane

4: 2,2,6,6-tetramethyl-piperidine-N-oxyl; [bis(acetoxy)iodo]benzene / water; dichloromethane / 3 h / 20 °C

With 2,2,6,6-tetramethyl-piperidine-N-oxyl; sodium tetrahydroborate; [bis(acetoxy)iodo]benzene; sodium methylate; tetra-(n-butyl)ammonium iodide; 2,4,6-tri-tert-butylpyrimidine; In methanol; ethanol; dichloromethane; water;
DOI:10.1021/jo302508e

Reference yield:

: 1421868-56-5
1,6-di-O-(tert-butyldiphenylsilyl)-2,5-di-O-(4-methoxybenzyl)-D-mannitol

: 1421868-59-8
1-O-(tert-butyldiphenylsilyl)-2-O-(4-methoxybenzyl)-sn-glyceryl 2,3,4-tri-O-benzyl-α-D-glucopyranosiduronic acid

Guidance literature:: Multi-step reaction with 5 steps

1: sodium periodate / water; tetrahydrofuran / 3 h / 20 °C

2: sodium tetrahydroborate / water; ethanol / 2 h / 0 °C

3: tetra-(n-butyl)ammonium iodide; 2,4,6-tri-tert-butylpyrimidine / dichloromethane / 144 h / 20 °C / Molecular sieve; Inert atmosphere

4: sodium methylate / methanol; dichloromethane

5: 2,2,6,6-tetramethyl-piperidine-N-oxyl; [bis(acetoxy)iodo]benzene / water; dichloromethane / 3 h / 20 °C

With 2,2,6,6-tetramethyl-piperidine-N-oxyl; sodium tetrahydroborate; sodium periodate; [bis(acetoxy)iodo]benzene; sodium methylate; tetra-(n-butyl)ammonium iodide; 2,4,6-tri-tert-butylpyrimidine; In tetrahydrofuran; methanol; ethanol; dichloromethane; water;
DOI:10.1021/jo302508e