Technology Process of C26H31FN2O2S
There total 5 articles about C26H31FN2O2S which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
3β-(4-methylphenyl)tropane-2β-N-4'-fluorophenacylcarboxamide ethylene ketal;
With
pyridine; trifluoromethylsulfonic anhydride;
In
dichloromethane;
at -45 - 0 ℃;
With
hydrogen sulfide;
In
dichloromethane;
at 0 ℃;
for 1h;
Further stages.;
DOI:10.1021/jm0703035
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: triphenylphosphine / tetrahydrofuran
1.2: 73 percent / water / tetrahydrofuran
2.1: 78 percent / 1-hydroxy-7-azabenzotriazole; 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide / dimethylformamide / 48 h / 25 °C
3.1: triflic anhydride; pyridine / CH2Cl2 / -45 - 0 °C
3.2: 66 percent / H2S / CH2Cl2 / 1 h / 0 °C
With
pyridine; 1-hydroxy-7-aza-benzotriazole; trifluoromethylsulfonic anhydride; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; triphenylphosphine;
In
tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
1.1: Staudinger reaction;
DOI:10.1021/jm0703035
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: 78 percent / 1-hydroxy-7-azabenzotriazole; 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide / dimethylformamide / 48 h / 25 °C
2.1: triflic anhydride; pyridine / CH2Cl2 / -45 - 0 °C
2.2: 66 percent / H2S / CH2Cl2 / 1 h / 0 °C
With
pyridine; 1-hydroxy-7-aza-benzotriazole; trifluoromethylsulfonic anhydride; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide;
In
dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm0703035
