2-ISOPROPENYLTHIAZOLE

Base Information

• Chemical Name: 2-ISOPROPENYLTHIAZOLE
• CAS No.: 13816-04-1
• Molecular Formula: C6H7 N S
• Molecular Weight: 125.194
• Hs Code.: 2934100090
• Mol file: 13816-04-1.mol

Synonyms:Thiazole,2-isopropenyl- (8CI); 2-Isopropenyl-1,3-thiazole; 2-Isopropenylthiazole

Chemical Property of 2-ISOPROPENYLTHIAZOLE

Chemical Property:

• Refractive Index: 1.5550 to 1.5570
• Boiling Point: 63 °C / 10mmHg
• Flash Point: 72.8oC
• PSA: 41.13000
• Density: 1,09 g/cm3
• LogP: 2.17620
• Storage Temp.: Freezer

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-Isopropenylthiazole (stabilized with HQ) ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

Useful:

Technology Process of 2-ISOPROPENYLTHIAZOLE

There total 2 articles about 2-ISOPROPENYLTHIAZOLE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-Acetylthiazole (24295-03-2,260998-74-1) + Methyltriphenylphosphonium bromide (1779-49-3) → 2-isopropenyl thiazole (13816-04-1)

Guidance literature:

Methyltriphenylphosphonium bromide; With potassium tert-butylate; In tetrahydrofuran; at 0 - 20 ℃; for 1h; Inert atmosphere;

2-Acetylthiazole; In tetrahydrofuran; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1039/d1cc04813a

Reference yield:

→ 2-isopropenyl thiazole (13816-04-1)

Guidance literature:

/BRN= 101227/;

DOI:10.1021/ma60005a015

Reference yield: 49.0%

2-isopropenyl thiazole (13816-04-1) + p-chlorophenylsulfonyl hydrazide (2751-25-9) → 2-(1-((4-chlorophenyl)sulfonyl)-2-fluoropropan-2-yl)thiazole

Guidance literature:

With diammonium phosphate; triethylamine tris(hydrogen fluoride); In dichloromethane; acetonitrile; at 20 ℃; for 4h; Inert atmosphere; Electrochemical reaction; Green chemistry;

DOI:10.1039/d1cc04813a

upstream raw materials:

2-Acetylthiazole

Methyltriphenylphosphonium bromide

Refernces

• 1、 Jiang, Yimin,Shi, Zhaojiang,Wu, Jinnan,Wu, Shaofen,Ye, Keyin,Yu, Yi,Yuan, Yaofeng. "Electrochemistry enabled selective vicinal fluorosulfenylation and fluorosulfoxidation of alkenes". supporting information. . Retrieved 2021/11/17.