5-METHYL-2-FURONITRILE

Base Information

• Chemical Name: 5-METHYL-2-FURONITRILE
• CAS No.: 13714-86-8
• Molecular Formula: C6H5 N O
• Molecular Weight: 107.112
• Hs Code.: 2932190090
• Mol file: 13714-86-8.mol

Synonyms:2-Furonitrile,5-methyl- (7CI,8CI); 2-Methyl-5-cyanofuran; 5-Methyl-2-cyanofuran;5-Methyl-2-furancarbonitrile; 5-Methyl-2-furonitrile; 5-Methyl-2-furyl cyanide

Chemical Property of 5-METHYL-2-FURONITRILE

Chemical Property:

• Vapor Pressure: 0.976mmHg at 25°C
• Refractive Index: n20/D 1.484(lit.)
• Boiling Point: 173-176 °C(lit.)
• Flash Point: 139 °F
• PSA: 36.93000
• Density: 1.02 g/mL at 25 °C(lit.)
• LogP: 1.45968

Purity/Quality:

98%,99%, ^*data from raw suppliers

5-methyl-2-furonitrile ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xn
• Statements: 20/21/22
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-METHYL-2-FURONITRILE

There total 20 articles about 5-METHYL-2-FURONITRILE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

5-Methylfurfural (620-02-0) → 5-methyl-furan-2-carbonitrile (13714-86-8)

Guidance literature:

With ammonium hydroxide; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; In acetonitrile; at 20 ℃; for 2h;

DOI:10.1016/j.tetlet.2007.03.137

Reference yield: 84.0%

(E)-2-(5-methylfuryl)aldehyde oxime (57784-58-4) → 5-methyl-furan-2-carbonitrile (13714-86-8)

Guidance literature:

With 2,2'-oxalyldi(o-sulfobenzimide); In acetonitrile; 1) r.t., 15 min, 2) reflux, 30 min;

DOI:10.1248/cpb.38.2583

Reference yield: 83.0%

5-methyl-2-furancarbaldehyde oxime → 5-methyl-furan-2-carbonitrile (13714-86-8)

Guidance literature:

With S,S-dimethyl dithiocarbonate; triethylamine; In 1,4-dioxane; at 90 ℃;

DOI:10.1055/s-2004-830878

upstream raw materials:

2-Chloromethylfuran

sodium cyanide

potassium cyanide

2-methylfuran

Downstream raw materials:

5-Methylfurfural

ethyl imidates of 5-methyl-2-furancarboxylic acid

2-chloromethyl-5-(5-methyl-2-furyl)-1,3,4-oxadiazole

5-methylfuran-2-carboximidamide

Refernces

• 1、 Jia, Xiuquan,Ma, Jiping,Wang, Min,Li, Xiaofang,Gao, Jin,Xu, Jie. "Alkali α-MnO2/Na: XMnO2 collaboratively catalyzed ammoxidation-Pinner tandem reaction of aldehydes". . p. 7429 - 7436. Retrieved 2016/10/21.
• 2、 Khan, Taukeer Ahmad,Peruncheralathan, Saravanan,Ila, Hiriyakkanavar,Junjappa, Hiriyakkanavar. "S,S-dimethyl dithiocarbonate: A useful reagent for efficient conversion of aldoximes to nitriles". . p. 2019 - 2021. Retrieved 2007/10/03.