C₁₉H₁₄F₂O₂

Base Information

• Chemical Name: C₁₉H₁₄F₂O₂
• CAS No.: 615563-94-5
• Molecular Formula: C₁₉H₁₄F₂O₂
• Molecular Weight: 312.316
• Mol file: 615563-94-5.mol

Synonyms:C₁₉H₁₄F₂O₂

Chemical Property of C₁₉H₁₄F₂O₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of C₁₉H₁₄F₂O₂

There total 2 articles about C₁₉H₁₄F₂O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 26.0%

p-fluorocinnamoyl-CoA (143246-49-5) + S-(hydrogen malonyl)coenzyme A (524-14-1) → C19H14F2O2 (615563-94-5)

Guidance literature:

With Huperzia serrata type III polyketide synthase; In aq. phosphate buffer; at 37 ℃; for 12h; pH=7; Enzymatic reaction;

DOI:10.1021/acs.orglett.6b01501

Reference yield:

4-fluorobenzaldehyde (459-57-4) + acetylacetone (123-54-6,81235-32-7) → C19H14F2O2 (615563-94-5)

Guidance literature:

4-fluorobenzaldehyde; With boric acid tributyl ester; In ethyl acetate; for 0.0833333h;

acetylacetone; With N-butylamine; boron trioxide; In ethyl acetate;

With hydrogenchloride; In water; ethyl acetate; at 60 ℃; for 1h;

DOI:10.1002/aoc.3685

Reference yield: 78.0%

[ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2 (52462-29-0) + C19H14F2O2 (615563-94-5) → C29H27ClF2O2Ru

Guidance literature:

With sodium ethanolate; In ethanol; at 20 ℃; for 1h;

DOI:10.1002/aoc.3685

upstream raw materials:

p-fluorocinnamoyl-CoA

S-(hydrogen malonyl)coenzyme A

4-fluorobenzaldehyde

acetylacetone