1-((4-methoxyphenyl)sulfonyl)-2-phenyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole

Base Information

Chemical Name:1-((4-methoxyphenyl)sulfonyl)-2-phenyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole
CAS No.:1261736-66-6
Molecular Formula:C₂₇H₂₈BNO₅S
Molecular Weight:489.4
Hs Code.:

Synonyms:1-((4-methoxyphenyl)sulfonyl)-2-phenyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole

Suppliers and Price of 1-((4-methoxyphenyl)sulfonyl)-2-phenyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-((4-methoxyphenyl)sulfonyl)-2-phenyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-((4-methoxyphenyl)sulfonyl)-2-phenyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole

There total 5 articles about 1-((4-methoxyphenyl)sulfonyl)-2-phenyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 76-09-5
2,3-dimethyl-2,3-butane diol

: C₂₇H₂₀BNO₅S

: 1261736-66-6
1-((4-methoxyphenyl)sulfonyl)-2-phenyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole

Guidance literature:: C₂₇H₂₀BNO₅S; With C₂₉H₃₇AuF₃N₂O; sodium 2,2,2-trifluoroacetate; In ⁽²⁾H₈-toluene; at 50 - 110 ℃; for 20h; Glovebox;

2,3-dimethyl-2,3-butane diol; With triethylamine; In toluene; at 80 ℃; for 20h; Glovebox;
DOI:10.1021/jacs.5b06678

Reference yield: 65.0%

: 946161-94-0
4-methoxy-N-(2-phenylethynyl-phenyl)-benzenesulfonamide

: 73183-34-3
bis(pinacol)diborane

: 1261736-66-6
1-((4-methoxyphenyl)sulfonyl)-2-phenyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole

Guidance literature:: With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; triphenyl-arsane; caesium carbonate; In N,N-dimethyl acetamide; at 60 ℃; for 0.5h; Inert atmosphere;
DOI:10.1039/c0cc03577g

Reference yield:

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

: 1261736-66-6
1-((4-methoxyphenyl)sulfonyl)-2-phenyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole

Guidance literature:: Multi-step reaction with 3 steps

1.1: pyridine / dichloromethane / 19.5 h / 20 °C

2.1: ⁽²⁾H₈-toluene / 20 h / 50 - 110 °C / Glovebox

3.1: C₂₉H₃₇AuF₃N₂O; sodium 2,2,2-trifluoroacetate / ⁽²⁾H₈-toluene / 20 h / 50 - 110 °C / Glovebox

3.2: 20 h / 80 °C / Glovebox

With pyridine; C₂₉H₃₇AuF₃N₂O; sodium 2,2,2-trifluoroacetate; In dichloromethane; ⁽²⁾H₈-toluene;
DOI:10.1021/jacs.5b06678