(3R,4R,5R)-3,4-di-(t-butyldimethylsilyloxy)-5-(t-butyldimethylsilyloxymethyl)cyclohexene

Base Information

Chemical Name:(3R,4R,5R)-3,4-di-(t-butyldimethylsilyloxy)-5-(t-butyldimethylsilyloxymethyl)cyclohexene
CAS No.:866916-68-9
Molecular Formula:C₂₅H₅₄O₃Si₃
Molecular Weight:486.958
Hs Code.:

Synonyms:(3R,4R,5R)-3,4-di-(t-butyldimethylsilyloxy)-5-(t-butyldimethylsilyloxymethyl)cyclohexene

Suppliers and Price of (3R,4R,5R)-3,4-di-(t-butyldimethylsilyloxy)-5-(t-butyldimethylsilyloxymethyl)cyclohexene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (3R,4R,5R)-3,4-di-(t-butyldimethylsilyloxy)-5-(t-butyldimethylsilyloxymethyl)cyclohexene

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (3R,4R,5R)-3,4-di-(t-butyldimethylsilyloxy)-5-(t-butyldimethylsilyloxymethyl)cyclohexene

There total 6 articles about (3R,4R,5R)-3,4-di-(t-butyldimethylsilyloxy)-5-(t-butyldimethylsilyloxymethyl)cyclohexene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 866916-83-8
(3R,4R,5R)-3,4-di-(t-butyldimethylsilyloxy)-5-(hydroxymethyl)cyclohexene

: 18162-48-6
tert-butyldimethylsilyl chloride

: 866916-68-9
(3R,4R,5R)-3,4-di-(t-butyldimethylsilyloxy)-5-(t-butyldimethylsilyloxymethyl)cyclohexene

Guidance literature:: With 1H-imidazole; In N,N-dimethyl-formamide; at 20 ℃; for 0.5h;
DOI:10.1081/CAR-200067125

Reference yield:

: (2R,3S,4R)-2-Vinyl-3,4-dihydro-2H-pyran-3,4-diol

: 866916-68-9
(3R,4R,5R)-3,4-di-(t-butyldimethylsilyloxy)-5-(t-butyldimethylsilyloxymethyl)cyclohexene

Guidance literature:: Multi-step reaction with 3 steps

1.1: 1.5 g / imidazole / dimethylformamide / 24 h / 60 °C

2.1: diphenyl ether / 2 h / 210 °C

2.2: 86 percent / sodium borohydride / tetrahydrofuran / 1 h / 20 °C

3.1: 91 percent / imidazole / dimethylformamide / 0.5 h / 20 °C

With 1H-imidazole; In diphenylether; N,N-dimethyl-formamide; 2.1: Claisen rearrangement;
DOI:10.1081/CAR-200067125

Reference yield:

: 866916-82-7
tri-O-acetyl-6,7-dideoxy-α-D-gluco-hept-6-enopyranosyl bromide

: 866916-68-9
(3R,4R,5R)-3,4-di-(t-butyldimethylsilyloxy)-5-(t-butyldimethylsilyloxymethyl)cyclohexene

Guidance literature:: Multi-step reaction with 5 steps

1.1: 92 percent / zinc; ammonium chloride; VO(salen) / methanol / 0.17 h

2.1: sodium methoxide / methanol / 0.5 h / 20 °C

3.1: 1.5 g / imidazole / dimethylformamide / 24 h / 60 °C

4.1: diphenyl ether / 2 h / 210 °C

4.2: 86 percent / sodium borohydride / tetrahydrofuran / 1 h / 20 °C

5.1: 91 percent / imidazole / dimethylformamide / 0.5 h / 20 °C

With 1H-imidazole; (N,N'-ethylenebis(salicylideneaminato))oxovanadium(IV); ammonium chloride; sodium methylate; zinc; In methanol; diphenylether; N,N-dimethyl-formamide; 4.1: Claisen rearrangement;
DOI:10.1081/CAR-200067125