(R)-8-((R)-3-(benzyloxy)-1-methoxypropyl)-10,10-diethyl-2,2,3,3,8-pentamethyl-4,9-dioxa-3,10-disiladodecane

Base Information

Chemical Name:(R)-8-((R)-3-(benzyloxy)-1-methoxypropyl)-10,10-diethyl-2,2,3,3,8-pentamethyl-4,9-dioxa-3,10-disiladodecane
CAS No.:1330118-89-2
Molecular Formula:C₂₈H₅₄O₄Si₂
Molecular Weight:510.905
Hs Code.:

Synonyms:(R)-8-((R)-3-(benzyloxy)-1-methoxypropyl)-10,10-diethyl-2,2,3,3,8-pentamethyl-4,9-dioxa-3,10-disiladodecane

Suppliers and Price of (R)-8-((R)-3-(benzyloxy)-1-methoxypropyl)-10,10-diethyl-2,2,3,3,8-pentamethyl-4,9-dioxa-3,10-disiladodecane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (R)-8-((R)-3-(benzyloxy)-1-methoxypropyl)-10,10-diethyl-2,2,3,3,8-pentamethyl-4,9-dioxa-3,10-disiladodecane

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (R)-8-((R)-3-(benzyloxy)-1-methoxypropyl)-10,10-diethyl-2,2,3,3,8-pentamethyl-4,9-dioxa-3,10-disiladodecane

There total 8 articles about (R)-8-((R)-3-(benzyloxy)-1-methoxypropyl)-10,10-diethyl-2,2,3,3,8-pentamethyl-4,9-dioxa-3,10-disiladodecane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 1330118-88-1
(5R,6R)-5-(2-(benzyloxy)ethyl)-3,3-diethyl-6,11,11,12,12-pentamethyl-4,10-dioxa-3,11-disilatridecan-6-ol

: 74-88-4
methyl iodide

: 1330118-89-2
(R)-8-((R)-3-(benzyloxy)-1-methoxypropyl)-10,10-diethyl-2,2,3,3,8-pentamethyl-4,9-dioxa-3,10-disiladodecane

Guidance literature:: With sodium hydride; In tetrahydrofuran; at 0 - 20 ℃; for 16h;
DOI:10.1021/jo201319b

Reference yield:

: 1254369-10-2
C₂₁H₃₈O₄Si

: 1330118-89-2
(R)-8-((R)-3-(benzyloxy)-1-methoxypropyl)-10,10-diethyl-2,2,3,3,8-pentamethyl-4,9-dioxa-3,10-disiladodecane

Guidance literature:: Multi-step reaction with 2 steps

1: 1H-imidazole / N,N-dimethyl-formamide / 1.5 h / 0 - 20 °C

2: sodium hydride / tetrahydrofuran / 16 h / 0 - 20 °C

With 1H-imidazole; sodium hydride; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1021/jo201319b

Reference yield:

: 117643-47-7
C₁₃H₁₈O₂

: 1330118-89-2
(R)-8-((R)-3-(benzyloxy)-1-methoxypropyl)-10,10-diethyl-2,2,3,3,8-pentamethyl-4,9-dioxa-3,10-disiladodecane

Guidance literature:: Multi-step reaction with 6 steps

1: propionic acid

2: lithium aluminium tetrahydride / diethyl ether

3: 1H-imidazole

4: AD-Mix-α

5: 1H-imidazole / N,N-dimethyl-formamide / 1.5 h / 0 - 20 °C

6: sodium hydride / tetrahydrofuran / 16 h / 0 - 20 °C

With 1H-imidazole; lithium aluminium tetrahydride; AD-Mix-α; sodium hydride; propionic acid; In tetrahydrofuran; diethyl ether; N,N-dimethyl-formamide; 1: Johnson-Claisen orthoester rearrangement / 4: Sharpless dihydroxylation;
DOI:10.1021/jo201319b