dithiocarbonic acid (1-{[acetyl-(4-fluorophenyl)-amino]-methyl}-5-chloro-4-oxo-pentyl) ester ethyl ester

Base Information

• Chemical Name: dithiocarbonic acid (1-{[acetyl-(4-fluorophenyl)-amino]-methyl}-5-chloro-4-oxo-pentyl) ester ethyl ester
• CAS No.: 877082-27-4
• Molecular Formula: C₁₇H₂₁ClFNO₃S₂
• Molecular Weight: 405.942
• Mol file: 877082-27-4.mol

Synonyms:dithiocarbonic acid (1-{[acetyl-(4-fluorophenyl)-amino]-methyl}-5-chloro-4-oxo-pentyl) ester ethyl ester

Chemical Property of dithiocarbonic acid (1-{[acetyl-(4-fluorophenyl)-amino]-methyl}-5-chloro-4-oxo-pentyl) ester ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of dithiocarbonic acid (1-{[acetyl-(4-fluorophenyl)-amino]-methyl}-5-chloro-4-oxo-pentyl) ester ethyl ester

There total 3 articles about dithiocarbonic acid (1-{[acetyl-(4-fluorophenyl)-amino]-methyl}-5-chloro-4-oxo-pentyl) ester ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

N-allyl-N-(4-fluoro-phenyl)acetamide (877082-19-4) + dithiocarbonic acid (3-chloro-2-oxo-propyl) ester ethyl ester (791096-00-9) → dithiocarbonic acid (1-{[acetyl-(4-fluorophenyl)-amino]-methyl}-5-chloro-4-oxo-pentyl) ester ethyl ester (877082-27-4)

Guidance literature:

With dilauryl peroxide; In 1,2-dichloro-ethane; Heating;

DOI:10.1039/b514509k

Reference yield:

4'-fluoroacetanilide (351-83-7) → dithiocarbonic acid (1-{[acetyl-(4-fluorophenyl)-amino]-methyl}-5-chloro-4-oxo-pentyl) ester ethyl ester (877082-27-4)

Guidance literature:

Multi-step reaction with 2 steps

1: NaOH

2: 80 percent / dilauroyl peroxide / 1,2-dichloro-ethane / Heating

With sodium hydroxide; dilauryl peroxide; In 1,2-dichloro-ethane;

DOI:10.1039/b514509k

Reference yield:

4-fluoroaniline (371-40-4) → dithiocarbonic acid (1-{[acetyl-(4-fluorophenyl)-amino]-methyl}-5-chloro-4-oxo-pentyl) ester ethyl ester (877082-27-4)

Guidance literature:

Multi-step reaction with 3 steps

1: NaOH

2: 80 percent / dilauroyl peroxide / 1,2-dichloro-ethane / Heating

With sodium hydroxide; dilauryl peroxide; In 1,2-dichloro-ethane;

DOI:10.1039/b514509k

upstream raw materials:

N-allyl-N-(4-fluoro-phenyl)acetamide

dithiocarbonic acid (3-chloro-2-oxo-propyl) ester ethyl ester

4'-fluoroacetanilide

4-fluoroaniline