4-(benzyloxy)-2,3-d1H ydro-1H-indole-2,3-dione

Base Information

• Chemical Name: 4-(benzyloxy)-2,3-d1H ydro-1H-indole-2,3-dione
• CAS No.: 1610457-25-4
• Molecular Formula: C₁₅H₁₁NO₃
• Molecular Weight: 253.257
• Mol file: 1610457-25-4.mol

Synonyms:4-(benzyloxy)-2,3-d1H ydro-1H-indole-2,3-dione

Chemical Property of 4-(benzyloxy)-2,3-d1H ydro-1H-indole-2,3-dione

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(benzyloxy)-2,3-d1H ydro-1H-indole-2,3-dione

There total 3 articles about 4-(benzyloxy)-2,3-d1H ydro-1H-indole-2,3-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

4-benzyloxy-1H-indole (20289-26-3) → 4-(benzyloxy)-2,3-d1H ydro-1H-indole-2,3-dione (1610457-25-4)

Guidance literature:

With tert.-butylhydroperoxide; iodine; In dimethyl sulfoxide; at 80 ℃; for 16h;

Reference yield:

1H-indol-4-ol (2380-94-1) → 4-(benzyloxy)-2,3-d1H ydro-1H-indole-2,3-dione (1610457-25-4)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / acetone / 20 h / 30 °C

2: iodine; tert.-butylhydroperoxide / dimethyl sulfoxide / 16 h / 80 °C

With tert.-butylhydroperoxide; iodine; potassium carbonate; In dimethyl sulfoxide; acetone;

Reference yield:

benzyl bromide (100-39-0) → 4-(benzyloxy)-2,3-d1H ydro-1H-indole-2,3-dione (1610457-25-4)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / acetone / 20 h / 30 °C

2: iodine; tert.-butylhydroperoxide / dimethyl sulfoxide / 16 h / 80 °C

With tert.-butylhydroperoxide; iodine; potassium carbonate; In dimethyl sulfoxide; acetone;

upstream raw materials:

4-benzyloxy-1H-indole

1H-indol-4-ol

benzyl bromide