Technology Process of (E)-3-(3-(2,6-dimethylstyryl)phenyl)propanal
There total 5 articles about (E)-3-(3-(2,6-dimethylstyryl)phenyl)propanal which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
tetrabutyl-ammonium chloride; palladium diacetate; sodium hydrogencarbonate;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 18h;
Inert atmosphere;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: methanol / 48 h / 20 °C
2.1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -78 - 20 °C
2.2: 1 h / -78 - 20 °C
3.1: palladium diacetate; sodium hydrogencarbonate; tetrabutyl-ammonium chloride / N,N-dimethyl-formamide / 18 h / 20 °C / Inert atmosphere
With
n-butyllithium; tetrabutyl-ammonium chloride; palladium diacetate; sodium hydrogencarbonate;
In
tetrahydrofuran; methanol; hexane; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -78 - 20 °C
1.2: 1 h / -78 - 20 °C
2.1: palladium diacetate; sodium hydrogencarbonate; tetrabutyl-ammonium chloride / N,N-dimethyl-formamide / 18 h / 20 °C / Inert atmosphere
With
n-butyllithium; tetrabutyl-ammonium chloride; palladium diacetate; sodium hydrogencarbonate;
In
tetrahydrofuran; hexane; N,N-dimethyl-formamide;
