5-phenylthiohexan-2-one

Base Information

• Chemical Name: 5-phenylthiohexan-2-one
• CAS No.: 884598-52-1
• Molecular Formula: C₁₂H₁₆OS
• Molecular Weight: 208.324
• Mol file: 884598-52-1.mol

Synonyms:5-phenylthiohexan-2-one

Chemical Property of 5-phenylthiohexan-2-one

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 5-phenylthiohexan-2-one

There total 1 articles about 5-phenylthiohexan-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

1,1-bis(phenylthio)ethane (13307-56-7) + methyl vinyl ketone (78-94-4,25038-87-3) → 5-phenylthiohexan-2-one (884598-52-1)

Guidance literature:

Multistep reaction;

DOI:10.1021/jo052535m

Reference yield: 85.0%

5-phenylthiohexan-2-one (884598-52-1) + trans-2-propenyl bromide (590-15-8) → (E)-4-Methyl-7-phenylsulfanyl-oct-2-en-4-ol

Guidance literature:

trans-2-propenyl bromide; With tert.-butyl lithium; In diethyl ether; cooling;

5-phenylthiohexan-2-one; In diethyl ether; cooling;

DOI:10.1021/jo052535m

Reference yield:

5-phenylthiohexan-2-one (884598-52-1) + Vinyl bromide (593-60-2,25951-54-6) → 3-methyl-6-(phenylthio)hept-1-en-3-ol (884598-54-3)

Guidance literature:

Vinyl bromide; With tert.-butyl lithium; In diethyl ether; at -78 - 0 ℃;

5-phenylthiohexan-2-one; In diethyl ether; cooling;

DOI:10.1021/jo052535m

upstream raw materials:

1,1-bis(phenylthio)ethane

methyl vinyl ketone

Downstream raw materials:

3-methyl-6-(phenylthio)hept-1-en-3-ol

Refernces