2-(4-(1,4,7,10-tetraoxa-13-azacyclopentadecan-13-yl)phenyl)-6-amino-1H-benzo[d,e]isoquinoline-1,3(2H)-dione

Base Information

• Chemical Name: 2-(4-(1,4,7,10-tetraoxa-13-azacyclopentadecan-13-yl)phenyl)-6-amino-1H-benzo[d,e]isoquinoline-1,3(2H)-dione
• CAS No.: 1286630-51-0
• Molecular Formula: C₂₈H₃₁N₃O₆
• Molecular Weight: 505.571
• Mol file: 1286630-51-0.mol

Synonyms:2-(4-(1,4,7,10-tetraoxa-13-azacyclopentadecan-13-yl)phenyl)-6-amino-1H-benzo[d,e]isoquinoline-1,3(2H)-dione

Chemical Property of 2-(4-(1,4,7,10-tetraoxa-13-azacyclopentadecan-13-yl)phenyl)-6-amino-1H-benzo[d,e]isoquinoline-1,3(2H)-dione

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(4-(1,4,7,10-tetraoxa-13-azacyclopentadecan-13-yl)phenyl)-6-amino-1H-benzo[d,e]isoquinoline-1,3(2H)-dione

There total 6 articles about 2-(4-(1,4,7,10-tetraoxa-13-azacyclopentadecan-13-yl)phenyl)-6-amino-1H-benzo[d,e]isoquinoline-1,3(2H)-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

2-(4-(1,4,7,10-tetraoxa-13-azacyclopentadecan-13-yl)phenyl)-6-nitro-1H-benzo[d,e]isoquinoline-1,3(2H)-dione → 2-(4-(1,4,7,10-tetraoxa-13-azacyclopentadecan-13-yl)phenyl)-6-amino-1H-benzo[d,e]isoquinoline-1,3(2H)-dione (1286630-51-0)

Guidance literature:

With hydrazine hydrate; In 1,4-dioxane; at 90 ℃; for 2h;

DOI:10.1016/j.dyepig.2013.03.008

Reference yield: 22.0%

2-(4-(1,4,7,10-tetraoxa-13-azacyclopentadecan-13-yl)phenyl)-6-nitro-1H-benzo[d,e]isoquinoline-1,3(2H)-dione → 2-(4-(1,4,7,10-tetraoxa-13-azacyclopentadecan-13-yl)phenyl)-6-amino-1H-benzo[d,e]isoquinoline-1,3(2H)-dione (1286630-51-0) + 2-(4-(1,4,7,10-tetraoxa-13-azacyclopentadecan-13-yl)phenyl)-6-amino-5-chloro-1H-benzo[d,e]isoquinoline-1,3(2H)-dione

Guidance literature:

With hydrogenchloride; tin(II) chloride dihdyrate; In ethanol; water; at 20 ℃; for 2h;

DOI:10.1016/j.dyepig.2013.03.008

Reference yield:

4-nitronaphthalic-1,8-anhydride (6642-29-1) → 2-(4-(1,4,7,10-tetraoxa-13-azacyclopentadecan-13-yl)phenyl)-6-amino-1H-benzo[d,e]isoquinoline-1,3(2H)-dione (1286630-51-0)

Guidance literature:

Multi-step reaction with 2 steps

1: acetic acid / 1.5 h / Reflux

2: hydrazine hydrate / 1,4-dioxane / 2 h / 90 °C

With hydrazine hydrate; acetic acid; In 1,4-dioxane;

DOI:10.1016/j.dyepig.2013.03.008

upstream raw materials:

4-nitronaphthalic-1,8-anhydride

N-(4-aminophenyl)-1,4,7,10-tetraoxa-13-azacyclopentadecane

Downstream raw materials:

C₃₇H₅₁N₃O₁₁Si