benzoic acid-O₁₈

Base Information

• Chemical Name: benzoic acid-O₁₈
• CAS No.: 21048-30-6
• Molecular Formula: C₇H₆O₂
• Molecular Weight: 124.124
• Mol file: 21048-30-6.mol

Synonyms:benzoic acid-O₁₈

Chemical Property of benzoic acid-O₁₈

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of benzoic acid-O₁₈

There total 38 articles about benzoic acid-O₁₈ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

benzoyl chloride (98-88-4) → 18O-benzoic acid (21048-30-6)

Guidance literature:

With pyridine; water; at 20 ℃; for 8h; Inert atmosphere;

DOI:10.1039/c8cc07328g

Reference yield: 18.0%

benzonitrile (100-47-0) → benzoic acid-O18 (21048-30-6)

Guidance literature:

With hydrogenchloride; ¹⁸O-labeled water; at 100 ℃; for 20h;

DOI:10.1007/s13361-016-1342-z

Reference yield:

C24H30N4NiO6*H2O → 18O-benzoic acid (21048-30-6) + salicylic acid (69-72-7,25496-36-0,8052-31-1)

Guidance literature:

With ¹⁸O-labeled water; In N,N-dimethyl-formamide; at 70 ℃;

DOI:10.1016/j.jinorgbio.2021.111632

upstream raw materials:

benzoyl chloride

1-Phenyl-4,4,4-trifluorobutane-1,3-dione

4,4-difluoro-1-phenyl-1,3-butanedione

1-phenylbutan-1,3-dione

Downstream raw materials:

phenyl <(18)O>benzoate

benzoic acid methyl ester

methyl [carbonyl-¹⁸O]benzoate

O¹⁸-benzamide

Refernces

• 1、 Allpress, Caleb J.,Grubel, Katarzyna,Szajna-Fuller, Ewa,Arif, Atta M.,Berreau, Lisa M.. "Regioselective aliphatic carbon-carbon bond cleavage by a model system of relevance to iron-containing acireductone dioxygenase". . p. 659 - 668. Retrieved 2013.
• 2、 Sánchez-Eguía, Brenda N.,Serrano-Plana, Joan,Company, Anna,Costas, Miquel. "Catalytic O2activation with synthetic models of α-ketoglutarate dependent oxygenases". . p. 14369 - 14372. Retrieved 2020.
• 3、 Soleymani Movahed, Farzaneh,Foo, Siong Wan,Mori, Shogo,Ogawa, Saeko,Saito, Susumu. "Phosphorus-Based Organocatalysis for the Dehydrative Cyclization of N-(2-Hydroxyethyl)amides into 2-Oxazolines". supporting information. p. 243 - 257. Retrieved 2021/12/17.