n-(2-Bromophenyl)-5-fluoro-1,3-dimethyl-1h-pyrazole-4-carboxamide

Base Information

Chemical Name:n-(2-Bromophenyl)-5-fluoro-1,3-dimethyl-1h-pyrazole-4-carboxamide
CAS No.:622383-91-9
Molecular Formula:C₁₂H₁₁BrFN₃O
Molecular Weight:312.141
Hs Code.:
DSSTox Substance ID:DTXSID601167425

Synonyms:SCHEMBL3029473;DTXSID601167425;n-(2-bromophenyl)-5-fluoro-1,3-dimethyl-1h-pyrazole-4-carboxamide;622383-91-9

Suppliers and Price of n-(2-Bromophenyl)-5-fluoro-1,3-dimethyl-1h-pyrazole-4-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of n-(2-Bromophenyl)-5-fluoro-1,3-dimethyl-1h-pyrazole-4-carboxamide

Chemical Property:

XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:311.00695
Heavy Atom Count:18
Complexity:318

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=NN(C(=C1C(=O)NC2=CC=CC=C2Br)F)C

Technology Process of n-(2-Bromophenyl)-5-fluoro-1,3-dimethyl-1h-pyrazole-4-carboxamide

There total 2 articles about n-(2-Bromophenyl)-5-fluoro-1,3-dimethyl-1h-pyrazole-4-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 1365265-12-8
N-(2-bromophenyl)-3-oxo-2-(trifluoromethyl)butanamide

: 60-34-4
methylhydrazine

: 622383-91-9
N-(2-bromophenyl)-5-fluoro-1,3-dimethylpyrazole-4-carboxamide

Guidance literature:: In ethanol; at 80 ℃; for 2h; Inert atmosphere;
DOI:10.1016/j.tet.2012.01.075

Reference yield:

: 52700-65-9
N-(2-bromophenyl)-3-oxobutanamide

: 622383-91-9
N-(2-bromophenyl)-5-fluoro-1,3-dimethylpyrazole-4-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: dihydrogen peroxide; iron(II) sulfate / water; dimethyl sulfoxide / 1 h / 20 °C / Inert atmosphere

2: ethanol / 2 h / 80 °C / Inert atmosphere

With dihydrogen peroxide; iron(II) sulfate; In ethanol; water; dimethyl sulfoxide;
DOI:10.1016/j.tet.2012.01.075