methyl (R)-4-(2-(1-(4-chloro-N-(2,5-difluorophenyl)phenylsulfonamido)ethyl)-5-fluorophenyl)butanoate

Base Information

Chemical Name:methyl (R)-4-(2-(1-(4-chloro-N-(2,5-difluorophenyl)phenylsulfonamido)ethyl)-5-fluorophenyl)butanoate
CAS No.:1240422-93-8
Molecular Formula:C₂₅H₂₃ClF₃NO₄S
Molecular Weight:525.976
Hs Code.:

Synonyms:methyl (R)-4-(2-(1-(4-chloro-N-(2,5-difluorophenyl)phenylsulfonamido)ethyl)-5-fluorophenyl)butanoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of methyl (R)-4-(2-(1-(4-chloro-N-(2,5-difluorophenyl)phenylsulfonamido)ethyl)-5-fluorophenyl)butanoate

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Technology Process of methyl (R)-4-(2-(1-(4-chloro-N-(2,5-difluorophenyl)phenylsulfonamido)ethyl)-5-fluorophenyl)butanoate

There total 1 articles about methyl (R)-4-(2-(1-(4-chloro-N-(2,5-difluorophenyl)phenylsulfonamido)ethyl)-5-fluorophenyl)butanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 18107-18-1
diazomethyl-trimethyl-silane

: 290315-45-6
(R)-4-(2-(1-(4-chloro-N-(2,5-difluorophenyl)phenylsulfonamido)ethyl)-5-fluorophenyl)butanoic acid

: 1240422-93-8
methyl (R)-4-(2-(1-(4-chloro-N-(2,5-difluorophenyl)phenylsulfonamido)ethyl)-5-fluorophenyl)butanoate

Guidance literature:: In methanol; toluene; at 50 ℃; Inert atmosphere;
DOI:10.1002/jlcr.1719

Reference yield: 59.0%

: 5707-04-0
Phenylselenyl chloride

: 1240422-93-8
methyl (R)-4-(2-(1-(4-chloro-N-(2,5-difluorophenyl)phenylsulfonamido)ethyl)-5-fluorophenyl)butanoate

: 1240422-95-0
methyl (R)-4-(2-(1-(4-chloro-N-(2,5-difluorophenyl)phenylsulfonamido)ethyl)-5-fluorophenyl)-2-(phenylselanyl)butanoate

Guidance literature:: methyl (R)-4-(2-(1-(4-chloro-N-(2,5-difluorophenyl)phenylsulfonamido)ethyl)-5-fluorophenyl)butanoate; With lithium hexamethyldisilazane; In tetrahydrofuran; at -78 ℃; Inert atmosphere;

Phenylselenyl chloride; In tetrahydrofuran; at -78 - 20 ℃; Inert atmosphere;
DOI:10.1002/jlcr.1719