methyl (R)-4-(2-(1-(4-chloro-N-(2,5-difluorophenyl)phenylsulfonamido)ethyl)-5-fluorophenyl)-2-(phenylselanyl)butanoate

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Chemical Name:methyl (R)-4-(2-(1-(4-chloro-N-(2,5-difluorophenyl)phenylsulfonamido)ethyl)-5-fluorophenyl)-2-(phenylselanyl)butanoate
CAS No.:1240422-95-0
Molecular Formula:C₃₁H₂₇ClF₃NO₄SSe
Molecular Weight:681.034
Hs Code.:

Synonyms:methyl (R)-4-(2-(1-(4-chloro-N-(2,5-difluorophenyl)phenylsulfonamido)ethyl)-5-fluorophenyl)-2-(phenylselanyl)butanoate

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Chemical Property of methyl (R)-4-(2-(1-(4-chloro-N-(2,5-difluorophenyl)phenylsulfonamido)ethyl)-5-fluorophenyl)-2-(phenylselanyl)butanoate

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Technology Process of methyl (R)-4-(2-(1-(4-chloro-N-(2,5-difluorophenyl)phenylsulfonamido)ethyl)-5-fluorophenyl)-2-(phenylselanyl)butanoate

There total 1 articles about methyl (R)-4-(2-(1-(4-chloro-N-(2,5-difluorophenyl)phenylsulfonamido)ethyl)-5-fluorophenyl)-2-(phenylselanyl)butanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

: 5707-04-0
Phenylselenyl chloride

: 1240422-93-8
methyl (R)-4-(2-(1-(4-chloro-N-(2,5-difluorophenyl)phenylsulfonamido)ethyl)-5-fluorophenyl)butanoate

: 1240422-95-0
methyl (R)-4-(2-(1-(4-chloro-N-(2,5-difluorophenyl)phenylsulfonamido)ethyl)-5-fluorophenyl)-2-(phenylselanyl)butanoate

Guidance literature:: methyl (R)-4-(2-(1-(4-chloro-N-(2,5-difluorophenyl)phenylsulfonamido)ethyl)-5-fluorophenyl)butanoate; With lithium hexamethyldisilazane; In tetrahydrofuran; at -78 ℃; Inert atmosphere;

Phenylselenyl chloride; In tetrahydrofuran; at -78 - 20 ℃; Inert atmosphere;
DOI:10.1002/jlcr.1719

Reference yield: 8.0%

: 1240422-95-0
methyl (R)-4-(2-(1-(4-chloro-N-(2,5-difluorophenyl)phenylsulfonamido)ethyl)-5-fluorophenyl)-2-(phenylselanyl)butanoate

: 1240422-97-2
methyl (R,E)-4-(2-(1-(4-chloro-N-(2,5-difluorophenyl)phenylsulfonamido)ethyl)-5-fluorophenyl)but-2-enoate

Guidance literature:: With dihydrogen peroxide; potassium hydrogencarbonate; In tetrahydrofuran; ethyl acetate; at 0 - 21 ℃;
DOI:10.1002/jlcr.1719