2-Amino-4-bromobutanoic acid

Base Information

• Chemical Name: 2-Amino-4-bromobutanoic acid
• CAS No.: 10364-50-8
• Molecular Formula: C₄H₈BrNO₂
• Molecular Weight: 182.017
• Hs Code.: 2922499990
• DSSTox Substance ID: DTXSID00405450
• Mol file: 10364-50-8.mol

Synonyms:2-amino-4-bromobutanoic acid;10364-50-8;Butanoic acid,2-amino-4-bromo-;SCHEMBL1763869;DTXSID00405450;AKOS006228879;CS-0440290

Chemical Property of 2-Amino-4-bromobutanoic acid

Chemical Property:

• Melting Point: 214-216℃
• PSA: 63.32000
• LogP: 0.88360
• Storage Temp.: 2-8°C
• XLogP3: -2.9
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 180.97384
• Heavy Atom Count: 8
• Complexity: 86.1

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-Amino-4-bromobutanoic acid 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(CBr)C(C(=O)O)N

Technology Process of 2-Amino-4-bromobutanoic acid

There total 1 articles about 2-Amino-4-bromobutanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-Amino-dihydro-furan-2-one (1192-20-7,2185-02-6,7686-01-3,51744-82-2) → 2-Amino-4-bromo-butyric acid (10364-50-8,63038-23-3,92136-58-8)

Guidance literature:

With hydrogen bromide;

DOI:10.1016/S0040-4039(01)80218-5

Reference yield:

methanol (67-56-1) + α-amino-γ-bromobutyric acid (10364-50-8) → methyl 2-amino-4-bromobutanoate (219752-67-7)

Guidance literature:

With thionyl chloride; at 12 - 20 ℃; for 20h;

Reference yield:

α-amino-γ-bromobutyric acid (10364-50-8) + di-tert-butyl dicarbonate (24424-99-5) → 2-(tert-butoxycarbonylamino)-4-hydroxy-butanoic acid (38308-92-8)

Guidance literature:

With sodium hydrogencarbonate; In 1,4-dioxane; water; at 0 - 20 ℃;

DOI:10.1021/jm8015798

upstream raw materials:

3-Amino-dihydro-furan-2-one

Downstream raw materials:

methyl 2-amino-4-bromobutanoate

2-(tert-butoxycarbonylamino)-4-hydroxy-butanoic acid

Refernces