Cyclopentanemethanol, 1-amino-, hydrogen sulfate (ester) (8CI)

Base Information

• Chemical Name: Cyclopentanemethanol, 1-amino-, hydrogen sulfate (ester) (8CI)
• CAS No.: 10316-99-1
• Molecular Formula: C6H13 N O4 S
• Molecular Weight: 195.23672
• Mol file: 10316-99-1.mol

Synonyms:Cyclopentanemethanol,1-amino-, hydrogen sulfate (7CI); Cyclopentanemethanol, 1-amino-, hydrogensulfate (ester) (8CI)

Chemical Property of Cyclopentanemethanol, 1-amino-, hydrogen sulfate (ester) (8CI)

Chemical Property:

• PKA: -3.34±0.18(Predicted)
• PSA: 98.00000
• Density: 1.387±0.06 g/cm3(Predicted)
• LogP: 1.85840

Purity/Quality:

98%,99%, ^*data from raw suppliers

(1-Aminocyclopentyl)methylhydrogensulfate 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Cyclopentanemethanol, 1-amino-, hydrogen sulfate (ester) (8CI)

There total 1 articles about Cyclopentanemethanol, 1-amino-, hydrogen sulfate (ester) (8CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

(1-aminocyclopentyl)methanol (10316-79-7) → (1-ammoniocyclopentyl)methyl sulfate (10316-99-1)

Guidance literature:

With chlorosulfonic acid; In acetonitrile; at 0 - 20 ℃; for 3.5h;

DOI:10.1021/jo302615g

Reference yield: 65.0%

(1-ammoniocyclopentyl)methyl sulfate (10316-99-1) + p-toluenesulfonyl chloride (98-59-9) → 1-(toluene-4-sulfonyl)-1-aza-spiro[2.4]heptane (548461-35-4)

Guidance literature:

(1-ammoniocyclopentyl)methyl sulfate; With sodium hydroxide; In water; toluene; for 18h; Reflux;

p-toluenesulfonyl chloride; With triethylamine; at 20 ℃; for 12h;

DOI:10.1021/jo302615g

Reference yield:

(1-ammoniocyclopentyl)methyl sulfate (10316-99-1) → (1-aminocyclopentyl)methanesulfonic acid (1016988-49-0)

Guidance literature:

With sodium sulfite; In water; Heating;

DOI:10.1055/s-2007-1000861

upstream raw materials:

(1-aminocyclopentyl)methanol

Downstream raw materials:

(1-aminocyclopentyl)methanesulfonic acid

1-(toluene-4-sulfonyl)-1-aza-spiro[2.4]heptane

Refernces

• 1、 Zhang, Wei,Wang, Boyuan,Chen, Ning,Du, Da-Ming,Xu, Jiaxi. "Expeditious and practical synthesis of various substituted taurines from amino alcohols". . p. 197 - 200. Retrieved 2008/12/20.