benzyl (+/-)-5-(2-methyl-1,3-dioxolan-2-yl)-2-hydroxypentanoate

Base Information

• Chemical Name: benzyl (+/-)-5-(2-methyl-1,3-dioxolan-2-yl)-2-hydroxypentanoate
• CAS No.: 90741-56-3
• Molecular Formula: C₁₆H₂₂O₅
• Molecular Weight: 294.348
• Mol file: 90741-56-3.mol

Synonyms:benzyl (+/-)-5-(2-methyl-1,3-dioxolan-2-yl)-2-hydroxypentanoate

Chemical Property of benzyl (+/-)-5-(2-methyl-1,3-dioxolan-2-yl)-2-hydroxypentanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of benzyl (+/-)-5-(2-methyl-1,3-dioxolan-2-yl)-2-hydroxypentanoate

There total 3 articles about benzyl (+/-)-5-(2-methyl-1,3-dioxolan-2-yl)-2-hydroxypentanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

benzyl-5-(2-methyl-1,3-dioxolan-2-yl)-2-oxopentanoate (90741-55-2) → benzyl (+/-)-5-(2-methyl-1,3-dioxolan-2-yl)-2-hydroxypentanoate (90741-56-3)

Guidance literature:

With hydrogen; triethylamine; platinum on activated charcoal; In ethyl acetate; for 0.266667h; under 2585.7 Torr; Yield given;

DOI:10.1021/ja00328a040

Reference yield:

ethylene-cetal de la bromo-5 pentanone-2 (24400-75-7) → benzyl (+/-)-5-(2-methyl-1,3-dioxolan-2-yl)-2-hydroxypentanoate (90741-56-3)

Guidance literature:

Multi-step reaction with 2 steps

2: Et₃N, H₂ / 5percent Pt/C / ethyl acetate / 0.27 h / 2585.7 Torr

With hydrogen; triethylamine; platinum on activated charcoal; In ethyl acetate;

DOI:10.1021/ja00328a040

Reference yield:

dibenzyl oxalate (7579-36-4) → benzyl (+/-)-5-(2-methyl-1,3-dioxolan-2-yl)-2-hydroxypentanoate (90741-56-3)

Guidance literature:

Multi-step reaction with 2 steps

2: Et₃N, H₂ / 5percent Pt/C / ethyl acetate / 0.27 h / 2585.7 Torr

With hydrogen; triethylamine; platinum on activated charcoal; In ethyl acetate;

DOI:10.1021/ja00328a040

upstream raw materials:

benzyl-5-(2-methyl-1,3-dioxolan-2-yl)-2-oxopentanoate

ethylene-cetal de la bromo-5 pentanone-2

dibenzyl oxalate

Downstream raw materials:

benzyl (+/-)-5-(2-methyl-1,3-dioxolan-2-yl)-2-<((trifluoromethyl)sulfonyl)oxy>pentanoate

(R)-1-benzyl-5-<4-(2-methyl-1,3-dioxolan-2-yl)-1-((benzyloxy)carbonyl)butylidene>proline tert-butyl ester