24400-75-7

Usage

Uses

Used in Chemical Synthesis:
2-Methyl-2-(3-bromopropyl)-1,3-dioxolane is used as a solvent in various chemical reactions for its ability to dissolve a range of substances, facilitating the process and improving reaction efficiency.
Used as an Intermediate:
In the chemical industry, 2-Methyl-2-(3-bromopropyl)-1,3-dioxolane serves as an intermediate in the synthesis of more complex organic compounds, contributing to the formation of desired end products through intermediate steps.
Used in Pharmaceutical Synthesis:
2-Methyl-2-(3-bromopropyl)-1,3-dioxolane is utilized as a precursor in the production of pharmaceuticals, playing a crucial role in the development of new drugs and medicines.
Used in Agrochemical Production:
2-Methyl-2-(3-bromopropyl)-1,3-dioxolane is also employed in the synthesis of agrochemicals, contributing to the development of products that protect crops and enhance agricultural productivity.
Used in Specialty Polymers and Resins:
2-Methyl-2-(3-bromopropyl)-1,3-dioxolane has potential applications in the production of specialty polymers and resins, where it can impart specific properties to the final materials, such as improved durability or chemical resistance.
Used in Chemical Research:
In the field of chemical research, 2-Methyl-2-(3-bromopropyl)-1,3-dioxolane is used to explore new chemical reactions and mechanisms, contributing to the advancement of scientific knowledge and the discovery of new compounds.

Upstream product

• 29021-98-5 3-(2-methyl-[1,3]dioxolan-2-yl)-propan-1-ol 

Downstream Products

• 928-39-2 hept-6-yn-2-one 
• 74040-00-9 (+)-17β-Benzoyloxy-4.5-seco-oestren-(9)-dion-(3.5) 
• 33489-57-5 2-(4-benzyloxy-pyrimidin-2-yl)-5-(2-methyl-[1,3]dioxolan-2-yl)-pentanoic acid ethyl ester 
• 103697-46-7 8-methyl-9-phenylthionon-7-en-2-one ethylene ketal 
• 90741-55-2 benzyl-5-(2-methyl-1,3-dioxolan-2-yl)-2-oxopentanoate 
• 86040-08-6 (4R,S,6S)-6-Benzyloxy-1-(2-methyl-1,3-dioxolan-2-yl)-4-heptanol 
• 86040-08-6 (4R,S,6R)-6-Benzyloxy-1-(2-methyl-1,3-dioxolan-2-yl)-4-heptanol 
• 79850-99-0 1-(2,6-Bis-methoxymethoxy-phenyl)-4-(2-methyl-[1,3]dioxolan-2-yl)-butan-1-ol 
• 83152-81-2 C₁₇⁽¹³⁾CH₂₈O₇ 
• 93662-62-5 2,2-ethylenedioxy-6-tosyl-6-hexadecyl isocyanide 
• 5944-33-2 (5-Brom-pentanon-(2)-aethylenacetal)-phosphoniumbromid 
• 87109-17-9 1-diphenylphosphinoyl-4-(2-methyl-[1,3]dioxolan-2-yl)-propane 
• 102357-46-0 (3S,4R)-3-Benzyloxy-7-(2-methyl-[1,3]dioxolan-2-yl)-2-trimethylsilanyl-hept-1-en-4-ol 
• 41305-06-0 5-(m-Methoxyphenoxy)-pentan-4-on 

Relevant academic research and scientific papers

GGA DERIVATIVES

This invention relates to geranylgeranyl acetone (GGA) derivatives, pharmaceutical compositions comprising GGA derivatives and the use of GGA derivatives.

METHODS FOR TREATING NEURON DAMAGE

This invention relates to the use of geranylgeranyl acetone (GGA), its isomers, and GGA derivatives in a method for for treating a disease in a subject mediated in part by miRNA-378 or miRNA-711 increased activity comprising administering to the subject a therapeutically effective amount of 5-trans-GGA or a derivative thereof.

GGA AND GGA DERIVATIVES COMPOSITIONS THEREOF AND METHODS FOR TREATING NEURODEGENERATIVE DISEASES INCLUDING PARALYSIS INCLUDING THEM

This invention relates to geranylgeranyl acetone (GGA) derivatives and the use of GGA, its isomers, and GGA derivatives in methods for inhibiting neural death, increasing neural activity, increasing axon growth and cell viability, and increasing the survival rate of subjects administered the GGA or GGA derivatives.

GGA AND GGA DERIVATIVES, COMPOSITIONS THEREOF AND METHODS FOR TREATING NEURODEGENERATIVE DISEASES INCLUDING PARALYSIS INCLUDING THEM

This invention relates to geranylgeranyl acetone (GGA) derivatives and the use of GGA, its isomers, and GGA derivatives in methods for inhibiting neural death, increasing neural activity, increasing axon growth and cell viability, and increasing the survival rate of subjects administered the GGA or GGA derivatives.

METHODS FOR TREATING NEURODEGENERATIVE DISEASES

This invention relates to the 5-cis and 5-trans isomers of geranylgeranyl acetone, preferably such synthetic isomers, and pharmaceutical compositions containing such isomers. Other aspects of this invention relate to the use of geranylgeranyl acetone and its isomers in methods for inhibiting neural death, increasing neural activity, and increasing axon growth and cell viability. Geranylgeranyl acetone is a known anti-ulcer drug used commercially and in clinical situations. GGA has also been shown to exert cytoprotective effects on a variety of organs, such as the eye, brain, and heart.

Synthesis of labelled [13C6]testosterone and [13C5]19-nortestosterone

The condensation of ethyl acetoacetate-13C4 and ethyl bromoacetate-13C2 afforded, in seven steps, (1,2,3,4,5-13C5) 5-(diethylphosphono)-2-pentanone ethylene ketal 9. The reaction of this labelled compound with 7-[[(1,1-dimethylethyl)-dimethylsilyl]oxy]-1,6,6a,7,8, 9, 9a, 9b-octahydro-6a-methyl-[6aS-(6aa,7a,9aβ,9ba)] cyclopenta[f][1]benzopyran-3 (2H)-one 13 gave the benzindenone 14 which was converted to (1,2,3,4,10,19-13C6)testosterone 17 then, into (1,2,3,4,10-13C5)19-nortestosterone 18 by a reductive alkylation method.

INSECT PHEROMONES AND THEIR ANALOGS. XLVII. SYNTHESIS OF 11-OXODODECA-3,6-DIYNOIC ACID - THE ACYCLIC PRECURSOR OF A MACROLIDE COMPONENT OF PHEROMONES OF Oryzaephilus mercator AND O. surinamensis

A new approach is proposed to the synthesis of 11-oxododeca-3,6-diynoic acid - the acyclic precursor of a macrolide component of pheromones of Oryzaephilus mercator and O. surinamensis - from the readily available tetrahydropyran or allylacetone via the intermediate 5-bromo-2,2-ethylenedioxypentane.

Convenient Synthetic Route tp 6,8-Dioxabicyclooctanes, the Aggregation Pheromone Components of Bark Beetles

Convenient syntheses of (+/-)-frontalin (I) and (+/-)-brevicomins (IIa) and (IIb) were achieved from pent-4-en-1-ol (2) and pent-4-yn-1-ol (3).In a few simple and unambiguous steps, the alkenol (2) and the alkynol (3) were transformed into the acetal bromide (7) and the alkenyl bromides (14) and (17), respectively.Acylation of Grignard reagents of these bromides provided the corresponding methyl ketones (8), (15), and (18), the key intermediates for the synthesis of the title bicyclic acetals.The ketone (8) was converted into the olefin (9) which, on epoxidation followed by acid hydrolysis, yielded (+/-)-frontalin, whereas epoxidation of the alkenones (15) and (18) and subsequent cyclization afforded exo- and endo-brevicomin, stereoselectively.