N-[4-[[(2-chloroquinazolin-4-yl)amino]methyl]phenyl]-4-fluorobenzamide

Base Information

Chemical Name:N-[4-[[(2-chloroquinazolin-4-yl)amino]methyl]phenyl]-4-fluorobenzamide
CAS No.:1039735-65-3
Molecular Formula:C₂₂H₁₆ClFN₄O
Molecular Weight:406.847
Hs Code.:

Synonyms:N-[4-[[(2-chloroquinazolin-4-yl)amino]methyl]phenyl]-4-fluorobenzamide

Suppliers and Price of N-[4-[[(2-chloroquinazolin-4-yl)amino]methyl]phenyl]-4-fluorobenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-[4-[[(2-chloroquinazolin-4-yl)amino]methyl]phenyl]-4-fluorobenzamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-[4-[[(2-chloroquinazolin-4-yl)amino]methyl]phenyl]-4-fluorobenzamide

There total 5 articles about N-[4-[[(2-chloroquinazolin-4-yl)amino]methyl]phenyl]-4-fluorobenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 926207-17-2
N-[4-(aminomethyl)phenyl]-4-fluorobenzamide

: 607-68-1
2,4-dichloroquinazoline

: 1039735-65-3
N-[4-[[(2-chloroquinazolin-4-yl)amino]methyl]phenyl]-4-fluorobenzamide

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃;

Reference yield:

: C₁₉H₂₁FN₂O₃

: 1039735-65-3
N-[4-[[(2-chloroquinazolin-4-yl)amino]methyl]phenyl]-4-fluorobenzamide

Guidance literature:: Multi-step reaction with 2 steps

1: trifluoroacetic acid / dichloromethane / 20 °C

2: triethylamine / tetrahydrofuran; dichloromethane / 20 °C

With triethylamine; trifluoroacetic acid; In tetrahydrofuran; dichloromethane;
DOI:10.1021/jm201494a

Reference yield:

: 403-43-0
4-fluorobenzoyl chloride

: 1039735-65-3
N-[4-[[(2-chloroquinazolin-4-yl)amino]methyl]phenyl]-4-fluorobenzamide

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine / dichloromethane / 4 h / 20 °C / Cooling with ice; Inert atmosphere

2: trifluoroacetic acid / dichloromethane / 20 °C

3: triethylamine / tetrahydrofuran; dichloromethane / 20 °C

With triethylamine; trifluoroacetic acid; In tetrahydrofuran; dichloromethane;
DOI:10.1021/jm201494a