Z-THR(TBU)-OSU

Base Information

• Chemical Name: Z-THR(TBU)-OSU
• CAS No.: 10068-65-2
• Molecular Formula: C20H26 N2 O7
• Molecular Weight: 406.436
• Mol file: 10068-65-2.mol

Synonyms:Succinimide,N-[[3-tert-butoxy-2-(carboxyamino)butyryl]oxy]-, benzyl ester, L- (8CI);Butyric acid, 3-tert-butoxy-2-(carboxyamino)-, 2-benzyl ester, O-succinimidoderiv., L-

Chemical Property of Z-THR(TBU)-OSU

Chemical Property:

• PSA: 111.24000
• LogP: 2.42100
• Storage Temp.: -15°C

Purity/Quality:

97% ^*data from raw suppliers

Z-Thr(tBu)-OSu ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Z-Thr(tBu)-OSu is a reactant in the preparation of a thymosin fragment.

Technology Process of Z-THR(TBU)-OSU

There total 1 articles about Z-THR(TBU)-OSU which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-hydroxy-pyrrolidine-2,5-dione (6066-82-6) + N-benzyloxycarbonyl-O-t-butyl-L-threonine (16966-09-9) → Z-Thr(But)-ONSu (10068-65-2)

Guidance literature:

With dicyclohexyl-carbodiimide; In tetrahydrofuran; at 0 ℃; for 1h;

DOI:10.1002/chem.201302732

Reference yield: 99.0%

L-glutamine (56-85-9,26700-71-0) + Z-Thr(But)-ONSu (10068-65-2) → Z-L-Thr(tBu)-L-Gln-OH (138541-15-8)

Guidance literature:

With sodium hydrogencarbonate; In 1,4-dioxane; water; for 48h; Ambient temperature;

Reference yield: 99.0%

Z-Thr(But)-ONSu (10068-65-2) + methyl (2S)-2-amino-3-phenylpropanoate hydrochloride (7524-50-7) → Z-Thr(But)-Phe-OMe (17115-07-0)

Guidance literature:

With triethylamine; In N,N-dimethyl-formamide; 1.) -5 deg C - 0 deg C, 1 h, 2.) room temperature, overnight;

DOI:10.1039/P19810002040

upstream raw materials:

1-hydroxy-pyrrolidine-2,5-dione

N-benzyloxycarbonyl-O-t-butyl-L-threonine

Downstream raw materials:

Z-L-Thr(tBu)-L-Gln-OH

Z-L-Thr(tBu)-L-Glu(OtBu)-OH

Z-Thr(Bu^t)-Thr(Bu^t)-OH

Z-L-Thr(tBu)-L-Gln-L-Glu(OtBu)-OH

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 10068-65-2 Z-THR(TBU)-OSU

Send

Send

Metric Ton KG G Pound L ML

Send

Send