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C26H21Cl2F3N2O3S2

Base Information
  • Chemical Name:C26H21Cl2F3N2O3S2
  • CAS No.:1311374-66-9
  • Molecular Formula:C26H21Cl2F3N2O3S2
  • Molecular Weight:601.498
  • Hs Code.:
C<sub>26</sub>H<sub>21</sub>Cl<sub>2</sub>F<sub>3</sub>N<sub>2</sub>O<sub>3</sub>S<sub>2</sub>

Synonyms:C26H21Cl2F3N2O3S2

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Chemical Property of C26H21Cl2F3N2O3S2
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Technology Process of C26H21Cl2F3N2O3S2

There total 17 articles about C26H21Cl2F3N2O3S2 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
4-((5-(2-(4-chloro-3-methoxyphenyl)propan-2-yl)-1-(4-fluorophenyl)-1H-imidazol-2-ylthio)methyl)-3,5-difluorobenzenamine; With hydrogenchloride; acetic acid; sodium nitrite; In water; at 4 - 6 ℃;
With sulfur dioxide; copper dichloride; In water; acetic acid; at 5 ℃;
Guidance literature:
Multi-step reaction with 9 steps
1.1: tetra-N-butylammonium tribromide / methanol; dichloromethane / 3 h / 0 - 20 °C
2.1: sodium azide / N,N-dimethyl-formamide / 0 - 20 °C
3.1: hydrogenchloride; hydrogen / platinum(IV) oxide / methanol; water / 5 h / 2068.65 - 3361.55 Torr
4.1: acetic acid / 4 h / Reflux
5.1: caesium carbonate / acetonitrile / 2 h
6.1: trifluoroacetic acid / dichloromethane / 0 - 20 °C
7.1: diphenyl phosphoryl azide; N-ethyl-N,N-diisopropylamine / toluene / 0 - 80 °C
8.1: trifluoroacetic acid / dichloromethane / 0 - 20 °C
9.1: hydrogenchloride; acetic acid; sodium nitrite / water / 4 - 6 °C
9.2: 5 °C
With hydrogenchloride; sodium azide; diphenyl phosphoryl azide; hydrogen; tetra-N-butylammonium tribromide; caesium carbonate; acetic acid; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; sodium nitrite; platinum(IV) oxide; In methanol; dichloromethane; water; N,N-dimethyl-formamide; toluene; acetonitrile;
Guidance literature:
Multi-step reaction with 10 steps
1.1: tetrahydrofuran / 2 h / -78 - 20 °C
2.1: tetra-N-butylammonium tribromide / methanol; dichloromethane / 3 h / 0 - 20 °C
3.1: sodium azide / N,N-dimethyl-formamide / 0 - 20 °C
4.1: hydrogenchloride; hydrogen / platinum(IV) oxide / methanol; water / 5 h / 2068.65 - 3361.55 Torr
5.1: acetic acid / 4 h / Reflux
6.1: caesium carbonate / acetonitrile / 2 h
7.1: trifluoroacetic acid / dichloromethane / 0 - 20 °C
8.1: diphenyl phosphoryl azide; N-ethyl-N,N-diisopropylamine / toluene / 0 - 80 °C
9.1: trifluoroacetic acid / dichloromethane / 0 - 20 °C
10.1: hydrogenchloride; acetic acid; sodium nitrite / water / 4 - 6 °C
10.2: 5 °C
With hydrogenchloride; sodium azide; diphenyl phosphoryl azide; hydrogen; tetra-N-butylammonium tribromide; caesium carbonate; acetic acid; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; sodium nitrite; platinum(IV) oxide; In tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide; toluene; acetonitrile;
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