3-(1-HYDROXYCYCLOHEXYL)-2-PROPYNOIC ACID

Base Information

Chemical Name:3-(1-HYDROXYCYCLOHEXYL)-2-PROPYNOIC ACID
CAS No.:25294-58-0
Molecular Formula:C₉H₁₂O₃
Molecular Weight:168.192
Hs Code.:
Mol file:25294-58-0.mol

Synonyms:3-(1-hydroxycyclohexyl)propiolic acid

Suppliers and Price of 3-(1-HYDROXYCYCLOHEXYL)-2-PROPYNOIC ACID

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
3-(1-Hydroxycyclohexyl)prop-2-ynoic acid
500mg
$ 359.00

Total 6 raw suppliers

Chemical Property of 3-(1-HYDROXYCYCLOHEXYL)-2-PROPYNOIC ACID

Chemical Property:

Melting Point:122-124.5 °C
Boiling Point:349.0±21.0 °C(Predicted)
PKA:2.45±0.10(Predicted)
Density:1.24±0.1 g/cm3(Predicted)

Purity/Quality:

98%min ^*data from raw suppliers

3-(1-Hydroxycyclohexyl)prop-2-ynoic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Statements: 36
Safety Statements: 26

MSDS Files:

Useful:

Technology Process of 3-(1-HYDROXYCYCLOHEXYL)-2-PROPYNOIC ACID

There total 6 articles about 3-(1-HYDROXYCYCLOHEXYL)-2-PROPYNOIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

: 76925-79-6
1-<2-(carboethoxy)-ethynyl>cyclohexanol

: 25294-58-0
3-(1-hydroxycyclohexyl)propiolic acid

Guidance literature:: With lithium hydroxide; In tetrahydrofuran; water; at 20 ℃; for 2h;
DOI:10.1021/acs.jmedchem.7b01351

Reference yield:

: 108-94-1,11119-77-0,9003-41-2,9075-99-4
cyclohexanone

: 922-67-8
propynoic acid methyl ester

: 25294-58-0
3-(1-hydroxycyclohexyl)propiolic acid

Guidance literature:: With diethyl ether; sodium amide; anschliessend mit wss. H₂SO₄ behandeln;
DOI:10.1021/ja01162a054

Reference yield:

: 108-94-1,11119-77-0,9003-41-2,9075-99-4
cyclohexanone

: 25294-58-0
3-(1-hydroxycyclohexyl)propiolic acid

Guidance literature:: Multi-step reaction with 2 steps

1: liquid NH₃

2: diethyl ether / anschliessend mit festem Kohlendioxid behandeln

With diethyl ether; ammonia;
DOI:10.1039/jr9460000503