Anhydro 8-ethyl-5-hydroxy-2-phenyl-7-oxo-1,3,4-oxadiazolo<3,2-a>pyrimidinium hydroxide

Base Information

• Chemical Name: Anhydro 8-ethyl-5-hydroxy-2-phenyl-7-oxo-1,3,4-oxadiazolo<3,2-a>pyrimidinium hydroxide
• CAS No.: 113966-37-3
• Molecular Formula: C₁₃H₁₁N₃O₃
• Molecular Weight: 257.249
• Mol file: 113966-37-3.mol

Synonyms:Anhydro 8-ethyl-5-hydroxy-2-phenyl-7-oxo-1,3,4-oxadiazolo<3,2-a>pyrimidinium hydroxide

Chemical Property of Anhydro 8-ethyl-5-hydroxy-2-phenyl-7-oxo-1,3,4-oxadiazolo<3,2-a>pyrimidinium hydroxide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Anhydro 8-ethyl-5-hydroxy-2-phenyl-7-oxo-1,3,4-oxadiazolo<3,2-a>pyrimidinium hydroxide

There total 5 articles about Anhydro 8-ethyl-5-hydroxy-2-phenyl-7-oxo-1,3,4-oxadiazolo<3,2-a>pyrimidinium hydroxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

carbon suboxide (504-64-3) + N-ethyl-5-phenyl-1,3,4-oxadiazole-2-amine (1617-98-7) → Anhydro 8-ethyl-5-hydroxy-2-phenyl-7-oxo-1,3,4-oxadiazolo<3,2-a>pyrimidinium hydroxide (113966-37-3)

Guidance literature:

In diethyl ether;

DOI:10.1002/jhet.5570240511

Reference yield: 31.0%

malonic acid bis-(2,4,6-trichloro-phenyl) ester (15781-70-1) + N-ethyl-5-phenyl-1,3,4-oxadiazole-2-amine (1617-98-7) → Anhydro 8-ethyl-5-hydroxy-2-phenyl-7-oxo-1,3,4-oxadiazolo<3,2-a>pyrimidinium hydroxide (113966-37-3) + 2,4,6-Trichlorophenol (88-06-2,67471-29-8)

Guidance literature:

at 160 ℃; for 0.0166667h;

DOI:10.1002/jhet.5570240511

Reference yield:

2-benzoyl-N-ethylhydrazinecarbothioamide (26257-93-2) → Anhydro 8-ethyl-5-hydroxy-2-phenyl-7-oxo-1,3,4-oxadiazolo<3,2-a>pyrimidinium hydroxide (113966-37-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 22 percent / methanol / 0.5 h / 60 °C

2: 62 percent / 3 h / 90 °C

3: 70 percent / diethyl ether

In methanol; diethyl ether;

DOI:10.1002/jhet.5570240511

upstream raw materials:

carbon suboxide

N-ethyl-5-phenyl-1,3,4-oxadiazole-2-amine

malonic acid bis-(2,4,6-trichloro-phenyl) ester

2-benzoyl-N-ethylhydrazinecarbothioamide