P-TOLYL-PHOSPHONIC ACID DIETHYL ESTER

Base Information

• Chemical Name: P-TOLYL-PHOSPHONIC ACID DIETHYL ESTER
• CAS No.: 1754-46-7
• Molecular Formula: C11H17 O3 P
• Molecular Weight: 228.228
• Hs Code.: 2931900090
• Mol file: 1754-46-7.mol

Synonyms:Phosphonicacid, (4-methylphenyl)-, diethyl ester (9CI); Phosphonic acid, p-tolyl-,diethyl ester (7CI,8CI); Diethyl (4-tolyl)phosphonate; Diethyl4-methylphenylphosphonate; Diethyl p-tolylphosphonate

Chemical Property of P-TOLYL-PHOSPHONIC ACID DIETHYL ESTER

Chemical Property:

• Vapor Pressure: 0.00228mmHg at 25°C
• Refractive Index: 1.483
• Boiling Point: 298.2°C at 760 mmHg
• Flash Point: 148.1°C
• PSA: 45.34000
• Density: 1.08g/cm³
• LogP: 2.88640

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of P-TOLYL-PHOSPHONIC ACID DIETHYL ESTER

There total 55 articles about P-TOLYL-PHOSPHONIC ACID DIETHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4-tolyl iodide (624-31-7) + phosphonic acid diethyl ester (762-04-9) → diethyl 4-methylphenylphosphonate (1754-46-7)

Guidance literature:

With Pd(PPh₂)(m-C₆H₄SO₃Na)*(H₂O)4; triethylamine; In water; acetonitrile; for 1.5h; Ambient temperature;

Reference yield: 96.0%

sodium 4-methylbenzenesulfinate (824-79-3) + phosphonic acid diethyl ester (762-04-9) → diethyl 4-methylphenylphosphonate (1754-46-7)

Guidance literature:

With silver carbonate; palladium dichloride; In dimethyl sulfoxide; N,N-dimethyl-formamide; at 120 ℃; for 0.166667h; Microwave irradiation;

DOI:10.1039/c4ra01270d

Reference yield: 94.0%

para-bromotoluene (106-38-7) + phosphonic acid diethyl ester (762-04-9) → diethyl 4-methylphenylphosphonate (1754-46-7)

Guidance literature:

With triethylamine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; at 90 ℃; for 17h;

DOI:10.1055/s-1981-29335

upstream raw materials:

toluene

4-tolyl iodide

triethyl phosphite

diethyl trimethylsilyl phosphate

Downstream raw materials:

(4-methylphenyl)phosphonic acid

p-tolylphosphonic dichloride

4-[[4-[bis(2-hydroxyethyl)amino]phenyl]diazenyl]-1-(4-phosphonobenzyl)pyridinium bromide

C₁₂H₁₆NO₃P