Dibenzhydryl disulfide

Base Information

• Chemical Name: Dibenzhydryl disulfide
• CAS No.: 1726-02-9
• Molecular Formula: C26H22 S2
• Molecular Weight: 398.593
• Hs Code.: 2930902000
• UNII: T5YG268UXJ
• DSSTox Substance ID: DTXSID70505951
• Nikkaji Number: J1.417.027H
• Wikidata: Q82361427
• Mol file: 1726-02-9.mol

Synonyms:Dibenzhydryl disulfide;1726-02-9;Disulfide, bis(diphenylmethyl);T5YG268UXJ;bis(diphenylmethyl) disulfide;[(benzhydryldisulfanyl)-phenylmethyl]benzene;UNII-T5YG268UXJ;bis(diphenylmethyl)disulfide;((Benzhydryldisulfanyl)-phenylmethyl)benzene;1,2-Dibenzhydryldisulfane;Bis-(diphenylmethyl)disulfide;SCHEMBL775058;DTXSID70505951;CS-0448547;FT-0742823;1,1',1'',1'''-(Disulfanediyldimethanetriyl)tetrabenzene;Bis(diphenylmethyl)disulfide;Modafinil Related Compound E

Chemical Property of Dibenzhydryl disulfide

Chemical Property:

• Melting Point: 153℃
• Boiling Point: 525.3±50.0 °C(Predicted)
• PSA: 50.60000
• Density: 1.177±0.06 g/cm3(Predicted)
• LogP: 7.94700
• XLogP3: 7.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 7
• Exact Mass: 398.11629305
• Heavy Atom Count: 28
• Complexity: 336

Purity/Quality:

98%Min ^*data from raw suppliers

DibenzhydrylDisulfide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(C2=CC=CC=C2)SSC(C3=CC=CC=C3)C4=CC=CC=C4
• Uses: Dibenzhydryl Disulfide (Modafinil USP Related Compound E) is an impurity in the synthesis of Modafinil, and is also used in reactions involving thioketones.

Technology Process of Dibenzhydryl disulfide

There total 33 articles about Dibenzhydryl disulfide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

diphenylchloromethane (90-99-3) → bis(diphenylmethyl)disulfide (1726-02-9)

Guidance literature:

With sodium hydroxide; sulfur; hydrazine hydrate; In N,N-dimethyl-formamide; at 20 ℃; for 6h;

DOI:10.1016/j.jorganchem.2004.07.040

Reference yield: 67.0%

C13H11O3S2(1-)*Na(1+) → bis(diphenylmethyl)disulfide (1726-02-9)

Guidance literature:

With 1H-imidazole; water; at 70 ℃; for 0.583333h; Green chemistry;

DOI:10.1080/10426507.2014.1003643

Reference yield: 49.0%

Thiobenzophenon (1450-31-3) → bis(diphenylmethyl)disulfide (1726-02-9)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran;

DOI:10.1002/1522-2675(200206)85:6<1644::AID-HLCA1644>3.0.CO;2-8

upstream raw materials:

benzophenone

1,1-Diphenylmethanol

Dichlorodiphenylmethane

diphenylmethanethiol

Downstream raw materials:

Thiobenzophenon

benzophenone

1,1,1,2-tetraphenylethane

hydrogen sulfide

Refernces

• 1、 Bacon,Koechling. "". . p. 5594,5599. Retrieved 1964.
• 2、 -. "AN IMPROVED PROCESS FOR THE PREPARATION OF ARMODAFINIL". Page/Page column 22. . Retrieved 2008/06/13.
• 3、 Mloston, Grzegorz,Prakash, G. K. Surya,Olah, George A.,Heimgartner, Heinz. "Studies on reactions of thioketones with trimethyl(trifluoromethyl)silane catalyzed by fluoride ions". . p. 1644 - 1658. Retrieved 2007/10/03.