Methoxycarbonylmethyldisulfanyl-acetic acid methyl ester

Base Information

• Chemical Name: Methoxycarbonylmethyldisulfanyl-acetic acid methyl ester
• CAS No.: 1665-64-1
• Molecular Formula: C6H10 O4 S2
• Molecular Weight: 210.275
• Hs Code.: 2930909090
• Mol file: 1665-64-1.mol

Synonyms:Aceticacid, 2,2'-dithiobis-, dimethyl ester (9CI); Acetic acid, dithiodi-, dimethylester (6CI,7CI,8CI); Bis(2-methoxy-2-oxoethyl) disulfide;Di(methoxycarbonylmethyl) disulfide; Dimethyl 2,2'-dithiobisacetate; Dimethyl2,2'-dithiodiacetate; Dimethyl 2,2'-dithiodiyldiacetate; Dimethyl3,4-dithiaadipate; Dimethyl dithiodiglycolate; Dithiodiacetic acid dimethyl ester;Methyl (2-methoxy-2-oxoethyldithio)acetate; NSC 638710

Chemical Property of Methoxycarbonylmethyldisulfanyl-acetic acid methyl ester

Chemical Property:

• PSA: 103.20000
• LogP: 0.71380

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Methoxycarbonylmethyldisulfanyl-acetic acid methyl ester

There total 5 articles about Methoxycarbonylmethyldisulfanyl-acetic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

1,10-dichloro-5-(4-nitrophenyl)dipyrromethene (1013388-00-5) + Methyl thioglycolate (2365-48-2) → methyl bis(thioacetate) (1665-64-1) + 1,9-bis(2-methoxycarbonylmethylthia)-5-(4-nitrophenyl)dipyrrin

Guidance literature:

With triethylamine; In acetonitrile; at 70 ℃; for 21h; Inert atmosphere;

DOI:10.1016/j.dyepig.2016.02.018

Reference yield: 49.0%

1,9-dichloro-5-phenyldipyrromethene (1394285-00-7) + Methyl thioglycolate (2365-48-2) → methyl bis(thioacetate) (1665-64-1) + 1,9-bis(methoxycarbonylmethylthia)-5-phenyldipyrrin

Guidance literature:

With triethylamine; In acetonitrile; at 65 ℃; for 48h; Inert atmosphere;

DOI:10.1016/j.dyepig.2016.02.018

Reference yield: 10.0%

Methyl thioglycolate (2365-48-2) + phenylacetylene (536-74-3) → methyl bis(thioacetate) (1665-64-1) + methyl styrylthioacetate (125065-59-0) + ((E)-Styrylsulfanyl)-acetic acid methyl ester (175911-36-1)

Guidance literature:

With 2,2-dimethoxy-2-phenylacetophenone; In dimethyl sulfoxide; at 20 - 40 ℃; optical yield given as %de; UV-irradiation;

DOI:10.1021/jo101906j

upstream raw materials:

Methyl thioglycolate

phenylacetylene

1,9-dichloro-5-phenyldipyrromethene

1,10-dichloro-5-(4-nitrophenyl)dipyrromethene

Downstream raw materials:

perhydro 1,2-dithia-5,8-diazecine-4,9-dione

disulfanediyldiacetic acid

S-methoxycarbonylmethyl benzothioate

octyldisulfanyl-acetic acid methyl ester

Refernces

• 1、 Khakina, Ekaterina A.,Peregudov, Alexander S.,Yurkova, Anastasiya A.,Piven, Natalya P.,Shestakov, Alexander F.,Troshin, Pavel A.. "Unusual multistep reaction of C70Cl10 with thiols producing C70[SR]5H". . p. 1215 - 1219. Retrieved 2016/03/01.
• 2、 Minozzi, Matteo,Monesi, Alessandro,Nanni, Daniele,Spagnolo, Piero,Marchetti, Nicola,Massi, Alessandro. "An insight into the radical thiol/yne coupling: The emergence of arylalkyne-tagged sugars for the direct photoinduced glycosylation of cysteine-containing peptides". experimental part. p. 450 - 459. Retrieved 2011/04/19.