5-Bromo-4-fluoro-2-hydroxybenzoic acid

Base Information

Chemical Name:5-Bromo-4-fluoro-2-hydroxybenzoic acid
CAS No.:1644-71-9
Molecular Formula:C7H4 Br F O3
Molecular Weight:235.009
Hs Code.:2918290000
European Community (EC) Number:872-072-9
DSSTox Substance ID:DTXSID90594140
Wikidata:Q82488891
Mol file:1644-71-9.mol

Synonyms:5-BROMO-4-FLUORO-2-HYDROXYBENZOIC ACID;1644-71-9;5-BROMO-4-FLUOROSALICYLIC ACID;C7H4BrFO3;Benzoic acid, 5-bromo-4-fluoro-2-hydroxy-;5-bromo-4-fluoro-2-hydroxy-benzoic acid;5-BROMO-4-FLUOROSALICYLICACID;SCHEMBL1976832;DTXSID90594140;AJOOCGAVXMXLLF-UHFFFAOYSA-N;AMY30335;MFCD08235149;AKOS016009635;AT11228;PS-11643;DB-064538;CS-0106498;EN300-226077;Z1269213699;5-Bromo-4-fluorosalicylic acid, 4-Bromo-2-carboxy-5-fluorophenol

Suppliers and Price of 5-Bromo-4-fluoro-2-hydroxybenzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
5-Bromo-4-fluoro-2-hydroxybenzoic acid 96%
1 g
$ 256.00

SynQuest Laboratories
5-Bromo-4-fluoro-2-hydroxybenzoic acid 96%
250 mg
$ 114.00

SynQuest Laboratories
5-Bromo-4-fluoro-2-hydroxybenzoic acid 96%
5 g
$ 797.00

Crysdot
5-Bromo-4-fluoro-2-hydroxybenzoicacid 95+%
5g
$ 823.00

Chemenu
5-bromo-4-fluoro-2-hydroxybenzoicacid 95%
5g
$ 777.00

Chemcia Scientific
5-Bromo-4-fluoro-2-hydroxy-benzoicacid 95%
5 G
$ 555.00

Chemcia Scientific
5-Bromo-4-fluoro-2-hydroxy-benzoicacid 95%
0.5 G
$ 140.00

Apolloscientific
5-Bromo-4-fluoro-2-hydroxybenzoicacid 96%
5g
$ 723.00

Apolloscientific
5-Bromo-4-fluoro-2-hydroxybenzoicacid 96%
1g
$ 232.00

Apolloscientific
5-Bromo-4-fluoro-2-hydroxybenzoicacid 96%
250mg
$ 103.00

Total 10 raw suppliers

Chemical Property of 5-Bromo-4-fluoro-2-hydroxybenzoic acid

Chemical Property:

Vapor Pressure:3.1E-05mmHg at 25°C
Melting Point:208 °C(Solv: ethanol (64-17-5))
Refractive Index:1.625
Boiling Point:341.4°Cat760mmHg
PKA:2.36±0.10(Predicted)
Flash Point:160.3°C
PSA：57.53000
Density:1.945g/cm³
LogP:1.99200
XLogP3:2.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:233.93278
Heavy Atom Count:12
Complexity:188

Purity/Quality:

99% ^*data from raw suppliers

5-Bromo-4-fluoro-2-hydroxybenzoic acid 96% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C(=CC(=C1Br)F)O)C(=O)O

Technology Process of 5-Bromo-4-fluoro-2-hydroxybenzoic acid

There total 4 articles about 5-Bromo-4-fluoro-2-hydroxybenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 345-29-9
4-fluorosalicylic acid

: 1644-71-9
5-bromo-4-fluoro-2-hydroxy-benzoic acid

Guidance literature:: With N-Bromosuccinimide; In N,N-dimethyl-formamide; at 18 ℃; for 24h;

Reference yield:

: 1583-58-0
2,4-difluoro-benzoic acid

: 1644-71-9
5-bromo-4-fluoro-2-hydroxy-benzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 68 percent / sodium hydroxide; 1,3-dimethyl-2-imidazolidinone / 4 h / 135 °C

2: 96 percent / N-bromosuccinimide / dimethylformamide / 24 h / 20 °C

With 1,3-dimethyl-2-imidazolidinone; sodium hydroxide; N-Bromosuccinimide; In N,N-dimethyl-formamide;
DOI:10.1016/j.bmc.2004.07.062