Ethanone, 2-chloro-1,2-bis(4-chlorophenyl)-

Base Information

• Chemical Name: Ethanone, 2-chloro-1,2-bis(4-chlorophenyl)-
• CAS No.: 71193-37-8
• Molecular Formula: C₁₄H₉Cl₃O
• Molecular Weight: 299.584
• DSSTox Substance ID: DTXSID801262106
• Mol file: 71193-37-8.mol

Synonyms:Ethanone, 2-chloro-1,2-bis(4-chlorophenyl)-;71193-37-8;SCHEMBL11752575;DTXSID801262106

Chemical Property of Ethanone, 2-chloro-1,2-bis(4-chlorophenyl)-

Chemical Property:

• XLogP3: 5.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 297.971898
• Heavy Atom Count: 18
• Complexity: 279

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC(=CC=C1C(C(=O)C2=CC=C(C=C2)Cl)Cl)Cl

Technology Process of Ethanone, 2-chloro-1,2-bis(4-chlorophenyl)-

There total 3 articles about Ethanone, 2-chloro-1,2-bis(4-chlorophenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

4,4'-dichlorobenzoin (4254-20-0) → 2-chloro-1,2-bis(4-chlorophenyl)ethanone (71193-37-8)

Guidance literature:

With thionyl chloride; N,N-dimethyl-formamide; In diethyl ether; for 0.5h; Ambient temperature;

Reference yield:

4-chlorobenzaldehyde (104-88-1) → 2-chloro-1,2-bis(4-chlorophenyl)ethanone (71193-37-8)

Guidance literature:

Multi-step reaction with 2 steps

1: methanol; potassium cyanide; H₂O

2: pyridine; SOCl₂ / 5 °C

With pyridine; methanol; potassium cyanide; thionyl chloride; water;

DOI:10.1021/ja01170a030

Reference yield:

→ 2-chloro-1,2-bis(4-chlorophenyl)ethanone (71193-37-8)

Guidance literature:

Li-Alkoxid 5a (R¹=R²=pCl-C6H4), Li-piperidid;

upstream raw materials:

4,4'-dichlorobenzoin

4-chlorobenzaldehyde

Downstream raw materials:

4,4'-dichloro-α-piperidino-deoxybenzoin

1,2-Bis-(4-chloro-phenyl)-2-p-tolylsulfanyl-ethanone

1,2-Bis-(4-chloro-phenyl)-2-(4-nitro-phenylsulfanyl)-ethanone

4,5-bis-(4-chlorophenyl)-2-aminothiazole