1-(bis(trimethylsilyl)methyl)-3-(3-methoxyphenyl)-1-methylurea

Base Information

• Chemical Name: 1-(bis(trimethylsilyl)methyl)-3-(3-methoxyphenyl)-1-methylurea
• CAS No.: 1042728-32-4
• Molecular Formula: C₁₆H₃₀N₂O₂Si₂
• Molecular Weight: 338.597
• Mol file: 1042728-32-4.mol

Synonyms:1-(bis(trimethylsilyl)methyl)-3-(3-methoxyphenyl)-1-methylurea

Chemical Property of 1-(bis(trimethylsilyl)methyl)-3-(3-methoxyphenyl)-1-methylurea

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 1-(bis(trimethylsilyl)methyl)-3-(3-methoxyphenyl)-1-methylurea

There total 1 articles about 1-(bis(trimethylsilyl)methyl)-3-(3-methoxyphenyl)-1-methylurea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 25.0%

chloro-trimethyl-silane (75-77-4) + 3-(3-methoxyphenyl)-1,1-dimethylurea (28170-54-9) → 3-(3-methoxyphenyl)-1-methyl-1-((trimethylsilyl)methyl)urea (1042728-46-0) + 1-(bis(trimethylsilyl)methyl)-3-(3-methoxyphenyl)-1-methylurea (1042728-32-4)

Guidance literature:

3-(3-methoxyphenyl)-1,1-dimethylurea; With tert.-butyl lithium; In tetrahydrofuran; pentane; at -78 ℃; for 2h;

chloro-trimethyl-silane; In tetrahydrofuran; pentane; at -78 - 20 ℃;

DOI:10.1002/anie.200800815

Reference yield: 90.0%

acrylic acid n-butyl ester (141-32-2,9003-49-0) + 1-(bis(trimethylsilyl)methyl)-3-(3-methoxyphenyl)-1-methylurea (1042728-32-4) → n-butyl crotonate (591-63-9,76754-49-9,7299-91-4)

Guidance literature:

With palladium diacetate; acetic acid; p-benzoquinone; at 60 ℃; for 2h;

DOI:10.1002/anie.200800815

upstream raw materials:

chloro-trimethyl-silane

3-(3-methoxyphenyl)-1,1-dimethylurea

Downstream raw materials:

n-butyl crotonate