Ethyl phenyl phosphinsaeurechlorid

Base Information

• Chemical Name: Ethyl phenyl phosphinsaeurechlorid
• CAS No.: 1499-22-5
• Molecular Formula: C8H10 Cl O P
• Molecular Weight: 188.594
• Hs Code.: 2903999090
• DSSTox Substance ID: DTXSID501292879
• Mol file: 1499-22-5.mol

Synonyms:1499-22-5;Ethyl phenyl phosphinsaeurechlorid;[chloro(ethyl)phosphoryl]benzene;ethylphenylphosphinic chloride;Phosphinic chloride, ethylphenyl-;SCHEMBL7364597;IHJRCKILKAJAQT-UHFFFAOYSA-N;DTXSID501292879;P-Ethyl-P-phenylphosphinic chloride;AKOS006330381

Chemical Property of Ethyl phenyl phosphinsaeurechlorid

Chemical Property:

• PSA: 26.88000
• LogP: 2.84870
• XLogP3: 2.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 188.0157796
• Heavy Atom Count: 11
• Complexity: 164

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCP(=O)(C1=CC=CC=C1)Cl

Technology Process of Ethyl phenyl phosphinsaeurechlorid

There total 11 articles about Ethyl phenyl phosphinsaeurechlorid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

ethylphenylphosphinic acid methyl ester (6829-76-1) → ethylphenylphosphinic chloride (1499-22-5)

Guidance literature:

With phosphorus pentachloride; In tetrachloromethane; for 3h; Heating;

DOI:10.1021/jo052575q

Reference yield: 88.0%

ethylphenylphosphinous chloride (15849-83-9,75231-38-8,75231-39-9) + trichloroacetic acid (76-03-9) → dichloroacethyl chloride (79-36-7) + ethylphenylphosphinic chloride (1499-22-5)

Guidance literature:

for 1h; Ambient temperature; argon atmosphere;

Reference yield: 85.0%

ethylphenylphosphinic acid ethyl ester (2227-43-2) → ethylphenylphosphinic chloride (1499-22-5)

Guidance literature:

With thionyl chloride; Heating;

DOI:10.1039/b007868i

upstream raw materials:

ethyl(phenyl)phosphinic acid

ethylphenylphosphinic acid ethyl ester

dichloro-acetic acid

ethyl ester of ethylphenylthiophosphinic acid

Downstream raw materials:

ethylphenylphosphinic acid methyl ester

S-methyl ethylphenylphosphinothioate

ethylphenylphosphinic azide

Aethyl-phenyl-thiopyrophosphinat