ethyl 4-[(4-cyclopropylisoquinolin-3-yl){[4-(trifluoromethoxy)phenyl]methyl}sulfamoyl]benzoate

Base Information

Chemical Name:ethyl 4-[(4-cyclopropylisoquinolin-3-yl){[4-(trifluoromethoxy)phenyl]methyl}sulfamoyl]benzoate
CAS No.:1400699-63-9
Molecular Formula:C₂₉H₂₅F₃N₂O₅S
Molecular Weight:570.589
Hs Code.:

Synonyms:ethyl 4-[(4-cyclopropylisoquinolin-3-yl){[4-(trifluoromethoxy)phenyl]methyl}sulfamoyl]benzoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of ethyl 4-[(4-cyclopropylisoquinolin-3-yl){[4-(trifluoromethoxy)phenyl]methyl}sulfamoyl]benzoate

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Technology Process of ethyl 4-[(4-cyclopropylisoquinolin-3-yl){[4-(trifluoromethoxy)phenyl]methyl}sulfamoyl]benzoate

There total 8 articles about ethyl 4-[(4-cyclopropylisoquinolin-3-yl){[4-(trifluoromethoxy)phenyl]methyl}sulfamoyl]benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 1400700-13-1
ethyl 4-({(4-bromoisoquinolin-3-yl)[4-(trifluoromethoxy)benzyl]amino}-sulfonyl)benzoate

: 411235-57-9
cyclopropylboronic acid

: 1400699-63-9
ethyl 4-[(4-cyclopropylisoquinolin-3-yl){[4-(trifluoromethoxy)phenyl]methyl}sulfamoyl]benzoate

Guidance literature:: With potassium phosphate; palladium diacetate; tricyclohexylphosphine; In water; toluene; at 100 ℃; for 5h; Inert atmosphere;

Reference yield: 10.0%

: 1400702-34-2
ethyl 4-({(4-iodoisoquinolin-3-yl)[4-(trifluoromethoxy)benzyl]amino}sulfonyl)benzoate

: 411235-57-9
cyclopropylboronic acid

: 1400699-63-9
ethyl 4-[(4-cyclopropylisoquinolin-3-yl){[4-(trifluoromethoxy)phenyl]methyl}sulfamoyl]benzoate

Guidance literature:: With potassium phosphate; palladium diacetate; tricyclohexylphosphine; In water; toluene; at 100 ℃; for 3.5h; Inert atmosphere;