[(E)-2-[4,5-bis(methoxycarbonyl)-6-methyl-9-(1-methylethyl)heptalen-1-yl]ethenyl]benzene

Base Information

• Chemical Name: [(E)-2-[4,5-bis(methoxycarbonyl)-6-methyl-9-(1-methylethyl)heptalen-1-yl]ethenyl]benzene
• CAS No.: 167259-07-6
• Molecular Formula: C₂₈H₂₈O₄
• Molecular Weight: 428.528
• Mol file: 167259-07-6.mol

Synonyms:[(E)-2-[4,5-bis(methoxycarbonyl)-6-methyl-9-(1-methylethyl)heptalen-1-yl]ethenyl]benzene

Chemical Property of [(E)-2-[4,5-bis(methoxycarbonyl)-6-methyl-9-(1-methylethyl)heptalen-1-yl]ethenyl]benzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [(E)-2-[4,5-bis(methoxycarbonyl)-6-methyl-9-(1-methylethyl)heptalen-1-yl]ethenyl]benzene

There total 4 articles about [(E)-2-[4,5-bis(methoxycarbonyl)-6-methyl-9-(1-methylethyl)heptalen-1-yl]ethenyl]benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 44.0%

dimethyl 1,6-dimethyl-9-(1-methylethyl)heptalene-4,5-dicarboxylate (98525-07-6,72898-39-6,98525-12-3,98525-13-4) + benzaldehyde (100-52-7) → [(E)-2-[4,5-bis(methoxycarbonyl)-6-methyl-9-(1-methylethyl)heptalen-1-yl]ethenyl]benzene (167259-07-6)

Guidance literature:

With potassium tert-butylate; In tetrahydrofuran; at 0 - 25 ℃; for 2h;

DOI:10.1002/(SICI)1522-2675(19991215)82:12<2260::AID-HLCA2260>3.0.CO;2-Z

Reference yield: 23.0%

tricarbonyl((6,7,8,9,10,10a-η)-[4,5-bis(methoxycarbonyl)-6-methyl-9-(1-methylethyl)-1-[(E)-2-phenylethenyl]]heptalene)chromium → [(E)-2-[4,5-bis(methoxycarbonyl)-6-methyl-9-(1-methylethyl)heptalen-1-yl]ethenyl]benzene (167259-07-6)

Guidance literature:

In further solvent(s); under Ar; Cr complex in HFB heated at 85-95°C for 24-60 h; cooled to room temp.; solvent evapd.; chromy. (SiO2, 20-30% Et2O in hexane);

DOI:10.1002/1522-2675(200204)85:4<1166::AID-HLCA1166>3.0.CO;2-U

Reference yield: 10.0%

dimethyl acetylenedicarboxylate (762-42-5) + 7-isopropyl-4-methyl-1-<(E)-2-phenylethenyl>azulene → dimethyl 7-isopropyl-4-methylazulene-1,2-dicarboxylate (72898-40-9) + dimethyl (E)-1-<5-isopropyl-8-methyl-3-<(E)-2-phenylethenyl>azulen-1-yl>ethene-1,2-dicarboxylate + dimethyl (Z)-1-<5-isopropyl-8-methyl-3-<(E)-2-phenylethenyl>azulen-1-yl>ethene-1,2-dicarboxylate + [(E)-2-[4,5-bis(methoxycarbonyl)-6-methyl-9-(1-methylethyl)heptalen-1-yl]ethenyl]benzene (167259-07-6)

Guidance literature:

With ; In acetonitrile; at 110 ℃; for 24h;

DOI:10.1002/hlca.19940770723

upstream raw materials:

dimethyl acetylenedicarboxylate

dimethyl 1,6-dimethyl-9-(1-methylethyl)heptalene-4,5-dicarboxylate

benzaldehyde