Methyl N-(trifluoroacetyl)-L-leucinate

Base Information

Chemical Name:Methyl N-(trifluoroacetyl)-L-leucinate
CAS No.:1115-39-5
Molecular Formula:C9H14 F3 N O3
Molecular Weight:241.21
Hs Code.:2924199090
DSSTox Substance ID:DTXSID40559744
Wikidata:Q82442578
Mol file:1115-39-5.mol

Synonyms:1115-39-5;Methyl N-(trifluoroacetyl)-L-leucinate;N-Trifluoroacetyl-L-leucine methyl ester;N-Trifluoroacetyl-L-leucine methyl ester;methyl (2S)-4-methyl-2-[(2,2,2-trifluoroacetyl)amino]pentanoate;SCHEMBL6675294;DTXSID40559744;l-Leucine, N-trifluoroacetyl-, methyl ester

Suppliers and Price of Methyl N-(trifluoroacetyl)-L-leucinate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
N-TRIFLUOROACETYL-L-LEUCINE METHYL ESTER 95.00%
5MG
$ 499.28

Total 7 raw suppliers

Chemical Property of Methyl N-(trifluoroacetyl)-L-leucinate

Chemical Property:

Boiling Point:227.25°C (rough estimate)
PSA：58.89000
LogP:2.09290
Storage Temp.:2-8°C
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:241.09257779
Heavy Atom Count:16
Complexity:263

Purity/Quality:

98%,99%, ^*data from raw suppliers

N-TRIFLUOROACETYL-L-LEUCINE METHYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)CC(C(=O)OC)NC(=O)C(F)(F)F
Isomeric SMILES:CC(C)C[C@@H](C(=O)OC)NC(=O)C(F)(F)F

Technology Process of Methyl N-(trifluoroacetyl)-L-leucinate

There total 8 articles about Methyl N-(trifluoroacetyl)-L-leucinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 2666-93-5
(S)-Leu-OMe

: 407-25-0
trifluoroacetic anhydride

: 1115-39-5
N-trifluoroacetyl methyl ester of (S)-leucine

Guidance literature:: With triethylamine; In dichloromethane; at -40 ℃;
DOI:10.1021/acs.orglett.5b00866

Reference yield:

: 886207-26-7
2,2,2-trifluoro-N-[3-methyl-1-(2-thioxo-oxazolidine-3-carbonyl)-butyl]-acetamide

: 67-56-1
methanol

: 2,2,2-trifluoro-N-[3-methyl-1-(2-thioxo-oxazolidine-3-carbonyl)-butyl]-acetamide

: 1115-39-5
N-trifluoroacetyl methyl ester of (S)-leucine

: 81083-98-9
N-TFA-D-Leu-OMe

Guidance literature:: With (1R)-1-{2-[(1S)-1-(NMe₂)ethyl]phenyl}-2,2,2-trifluoroethanol; In ⁽²⁾H₈-toluene; at -26 ℃; for 25h;
DOI:10.1021/ja058010t