(R,E)-2-(3-methylbut-1-enyl)-4-tosylmorpholine

Base Information

Chemical Name:(R,E)-2-(3-methylbut-1-enyl)-4-tosylmorpholine
CAS No.:1268368-73-5
Molecular Formula:C₁₆H₂₃NO₃S
Molecular Weight:309.43
Hs Code.:

Synonyms:(R,E)-2-(3-methylbut-1-enyl)-4-tosylmorpholine

Suppliers and Price of (R,E)-2-(3-methylbut-1-enyl)-4-tosylmorpholine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (R,E)-2-(3-methylbut-1-enyl)-4-tosylmorpholine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (R,E)-2-(3-methylbut-1-enyl)-4-tosylmorpholine

There total 4 articles about (R,E)-2-(3-methylbut-1-enyl)-4-tosylmorpholine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 1268368-61-1
(R,E)-N-(4-hydroxy-5-methylhex-2-enyl)-N-(2-hydroxyethyl)-4-methylbenzenesulfonamide

: 1268368-73-5
(R,E)-2-(3-methylbut-1-enyl)-4-tosylmorpholine

Guidance literature:: With triphenylphosphine gold (I) chloride; silver trifluoromethanesulfonate; In dichloromethane; at 20 ℃; for 3h; optical yield given as %ee; stereoselective reaction; Molecular sieve; Inert atmosphere;
DOI:10.1021/ol200203k

Reference yield:

: 1015445-11-0
4-methyl-N-[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]ethyl]-N-(2-propynyl)benzenesulfonamide

: 1268368-73-5
(R,E)-2-(3-methylbut-1-enyl)-4-tosylmorpholine

Guidance literature:: Multi-step reaction with 4 steps

1.1: (1S,2R)-(+)-N-methylephedrine; zinc trifluoromethanesulfonate; triethylamine / toluene / 0.25 h / 20 °C / Inert atmosphere

1.2: 24 h / 20 °C / Inert atmosphere

2.1: lithium aluminium tetrahydride / tetrahydrofuran / 3 h / 0 °C / Inert atmosphere

3.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 16 h / 0 °C / Inert atmosphere

4.1: triphenylphosphine gold (I) chloride; silver trifluoromethanesulfonate / dichloromethane / 3 h / 20 °C / Molecular sieve; Inert atmosphere

With lithium aluminium tetrahydride; triphenylphosphine gold (I) chloride; (1S,2R)-(+)-N-methylephedrine; tetrabutyl ammonium fluoride; silver trifluoromethanesulfonate; zinc trifluoromethanesulfonate; triethylamine; In tetrahydrofuran; dichloromethane; toluene;
DOI:10.1021/ol200203k

Reference yield:

: C₂₂H₃₉NO₄SSi

: 1268368-73-5
(R,E)-2-(3-methylbut-1-enyl)-4-tosylmorpholine

Guidance literature:: Multi-step reaction with 2 steps

1: tetrabutyl ammonium fluoride / tetrahydrofuran / 16 h / 0 °C / Inert atmosphere

2: triphenylphosphine gold (I) chloride; silver trifluoromethanesulfonate / dichloromethane / 3 h / 20 °C / Molecular sieve; Inert atmosphere

With triphenylphosphine gold (I) chloride; tetrabutyl ammonium fluoride; silver trifluoromethanesulfonate; In tetrahydrofuran; dichloromethane;
DOI:10.1021/ol200203k