N-(4-bromophenyl)-N-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-4,6-dichloropyrimidine-5-carboxamide

Base Information

Chemical Name:N-(4-bromophenyl)-N-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-4,6-dichloropyrimidine-5-carboxamide
CAS No.:1338326-87-6
Molecular Formula:C₁₉H₂₄BrCl₂N₃O₂Si
Molecular Weight:505.314
Hs Code.:

Synonyms:N-(4-bromophenyl)-N-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-4,6-dichloropyrimidine-5-carboxamide

Suppliers and Price of N-(4-bromophenyl)-N-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-4,6-dichloropyrimidine-5-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of N-(4-bromophenyl)-N-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-4,6-dichloropyrimidine-5-carboxamide

Chemical Property:

Boiling Point:545.5±50.0 °C(Predicted)
Density:1.361±0.06 g/cm3(Predicted)

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of N-(4-bromophenyl)-N-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-4,6-dichloropyrimidine-5-carboxamide

There total 4 articles about N-(4-bromophenyl)-N-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-4,6-dichloropyrimidine-5-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1338326-88-7
4-bromo-N-[2-[tert-butyl(dimethyl)silyl]oxyethyl]aniline

: 87600-97-3
4,6-dichloropyrimidine-5-carboxylic acid chloride

: 1338326-87-6
N-(4-bromophenyl)-N-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-4,6-dichloropyrimidine-5-carboxamide

Guidance literature:: With triethylamine; In tetrahydrofuran; at 0 ℃; for 2.01667h; Inert atmosphere;

Reference yield:

: 106-40-1
4-bromo-aniline

: 1338326-87-6
N-(4-bromophenyl)-N-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-4,6-dichloropyrimidine-5-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: sodium carbonate / N,N-dimethyl-formamide / 72 h / 60 °C / Inert atmosphere

2: triethylamine / tetrahydrofuran / 2.02 h / 0 °C / Inert atmosphere

With sodium carbonate; triethylamine; In tetrahydrofuran; N,N-dimethyl-formamide;

Reference yield:

: 86864-60-0
2-(tert-butyldimethylsilyloxy)ethyl bromide

: 1338326-87-6
N-(4-bromophenyl)-N-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-4,6-dichloropyrimidine-5-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: sodium carbonate / N,N-dimethyl-formamide / 72 h / 60 °C / Inert atmosphere

2: triethylamine / tetrahydrofuran / 2.02 h / 0 °C / Inert atmosphere

With sodium carbonate; triethylamine; In tetrahydrofuran; N,N-dimethyl-formamide;