(S)-2-((R)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionyloxy)-succinic acid dimethyl ester

Base Information

Chemical Name:(S)-2-((R)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionyloxy)-succinic acid dimethyl ester
CAS No.:76905-12-9
Molecular Formula:C₁₆H₁₇F₃O₇
Molecular Weight:378.302
Hs Code.:

Synonyms:(S)-2-((R)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionyloxy)-succinic acid dimethyl ester

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Chemical Property of (S)-2-((R)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionyloxy)-succinic acid dimethyl ester

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Technology Process of (S)-2-((R)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionyloxy)-succinic acid dimethyl ester

There total 7 articles about (S)-2-((R)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionyloxy)-succinic acid dimethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 67-56-1
methanol

: sarglabolide J

: 39637-99-5,20445-33-4
(S)-(+)-2-methoxy-2-trifluoromethyl-2-phenylacetyl chloride

: C₁₆H₁₇F₃O₅

: 76905-12-9
(S)-2-((R)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionyloxy)-succinic acid dimethyl ester

Guidance literature:: sarglabolide J; With water; potassium carbonate; In methanol; at 60 ℃; for 2h;

methanol; With thionyl chloride; at 20 ℃; for 12h;

(S)-(+)-2-methoxy-2-trifluoromethyl-2-phenylacetyl chloride; With pyridine;
DOI:10.1016/j.tet.2015.05.112

Reference yield:

: 67-56-1
methanol

: sarglabolide D

: 39637-99-5,20445-33-4
(S)-(+)-2-methoxy-2-trifluoromethyl-2-phenylacetyl chloride

: C₁₆H₁₇F₃O₅

: 76905-12-9
(S)-2-((R)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionyloxy)-succinic acid dimethyl ester

Guidance literature:: sarglabolide D; With water; potassium carbonate; In methanol; at 60 ℃; for 2h;

methanol; With thionyl chloride; at 20 ℃; for 12h;

(S)-(+)-2-methoxy-2-trifluoromethyl-2-phenylacetyl chloride; With pyridine;
DOI:10.1016/j.tet.2015.05.112

Reference yield:

: 67-56-1
methanol

: sarglabolide C

: 39637-99-5,20445-33-4
(S)-(+)-2-methoxy-2-trifluoromethyl-2-phenylacetyl chloride

: C₁₆H₁₇F₃O₅

: 76905-12-9
(S)-2-((R)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionyloxy)-succinic acid dimethyl ester

Guidance literature:: sarglabolide C; With water; potassium carbonate; In methanol; at 60 ℃; for 2h;

methanol; With thionyl chloride; at 20 ℃; for 12h;

(S)-(+)-2-methoxy-2-trifluoromethyl-2-phenylacetyl chloride; With pyridine;
DOI:10.1016/j.tet.2015.05.112